CHRND (NM_000751) Human 3' UTR Clone

Specifications

Product Data
Product Name	CHRND (NM_000751) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	ACHRD; CMS2A; CMS3A; CMS3B; CMS3C; FCCMS; SCCMS
ACCN	NM_000751
Insert Size	1382 bp
Sequence Data	Insert Sequence (showhide) >SC201945 3’UTR clone of NM_000751 The sequence shown below is from the reference sequence of NM_000751. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC TACAACGTGCAGGACAAGCGCTTCATCTAGGGTGGGCCTGTTGGGGAGCCAGGAGACAGCAGGGTCTGA GAGAGGAGCCACAGTCCCTAATGACACCCACTCCTAGCCCTGAGGCTCGTGCCCCTCAGACTGGGGAAG AGTCCAAGGAAGGGAGGGAGCAGCCACTCCTCAATGCTCAATGGCTCCCCTGAAATCAAGACAGGGGCC ACCCGAGATGGTCTGAGGGTGGACATCGGCTACAGTGGGTGGGCAGGACGATTTGGGGGGAGGCCCGAG GCTGGCTCAGGGGCCAGGGAGGAGGCCACTCAGGGTGGCCTCAGGGGGAGAGCTCTGATAGGGGTGAGA CAGATAGGGCCCCTTCTCTGCTTCTCCTCCCCCAAGGTGTGGGGTAGAGCAGGCAGGAATCTGCGCCTT CACTCTCTGGCCCCTCCAGCCTCCCTCTTCCTACCTACCCTTCAACCTCAGGCTTCTGAGGCCTCACCT GGGACTGAGGTTGAGGACACCTCCCTCCCTCCAGACCCCAGAGTATCCTTTCCTAGCTCTTTCTGCCTT GACCTCTCTGCCTAGGTCCCTTTGGGAAGTTGAGGACTGGAGTGGAAAGGTCAGGATCGACATCCACAA AGACTTGGGGTCAGCCTGAGGTTGCACACACAATCCTAGAGGACCAGAACGCAGCACCTCTCCCCAAAG GGTCCCTGCCCCCCAGCACCTACTCCTCTCCAAATTAGGGTTGTCATGCATTATTTGGGGCATACATAT TCTAAAAAATCATTCGTTGTTTCTCTGAAATTTGTCCCCTATTTTTATTTGCTAAATCTAGCAACCCTA TCCCAAAGGCAGCCTCCACTCAATCTTATCCTGAGGGCCAAAGGCCAAGGCTGCAGGAATTGGGAGACA AGGGTCTGTTTGTATGGTGGTCCACCTCCAAGATGGCCCCAGTGATGCCCAGTATTCACACCCTTGTGC AGTCCCCTCACTCTGTACCAGGGTGGGTCTGGGTAACCAATAGAATGAGGCAGAAGTGATGGTACCTCA CTTCCCAGATTTGGTTAGGAAAGACACTATGGCCTCTTTCTTGCTCATTAGCCCTCATTCTCACATCAG TTGGATCTCTCACTTTGGGGAAGCCAGCTGGCATGTTAAGGAGCCCTATGGAGAGGCCCACATGGCAAG GAACTAAGGCCTCCTGCCAACAGCCACGTGAGTGAATGTGGAAGTGGATCCTCTGCCCCAGTAGGGCCT TCGGATGAGATCACAGCCCAGTAGACATCTTATGTGCAGCCCCATGAAAGTCCCTAAGCCAGAACCACC AGCTAAGTGACTCCTGGATTCCTGACCCCCAGAAACTGTGTGAGATAATAAATGTGTGTTGTTTTAAGT GA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_000751.3
Synonyms	ACHRD; CMS2A; CMS3A; CMS3B; CMS3C; FCCMS; SCCMS
Summary	The acetylcholine receptor of muscle has 5 subunits of 4 different types: 2 alpha and 1 each of beta, gamma and delta subunits. After acetylcholine binding, the receptor undergoes an extensive conformation change that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. Defects in this gene are a cause of multiple pterygium syndrome lethal type (MUPSL), congenital myasthenic syndrome slow-channel type (SCCMS), and congenital myasthenic syndrome fast-channel type (FCCMS). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2015]
Locus ID	1144
MW	49.9

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