VIRMA (NM_183009) Human 3' UTR Clone

Specifications

Product Data
Product Name	VIRMA (NM_183009) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	fSAP121; KIAA1429; MSTP054
ACCN	NM_183009
Insert Size	183 bp
Sequence Data	Insert Sequence (showhide) >SC201980 3’UTR clone of NM_183009 The sequence shown below is from the reference sequence of NM_183009. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CTTATAAATGACTGCAGTAACACTTTTTAAAAAGCCAGTGATTTTGTTAAAAAACAAAAACCCTCATCT CCCTTCCTCCCAAAAAGACATAAAATAACCGGATGAGGGGGAGATAAAACTGAAACAAGTTGGTCATTG AGGAAATATGGGGGTAACATTTTAAATAAATTTTTGTTAAAGTGA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_183009.3
Synonyms	fSAP121; KIAA1429; MSTP054
Summary	Associated component of the WMM complex, a complex that mediates N6-methyladenosine (m6A) methylation of RNAs, a modification that plays a role in the efficiency of mRNA splicing and RNA processing (PubMed:24981863, PubMed:29507755). Acts as a key regulator of m6A methylation by promoting m6A methylation of mRNAs in the 3' UTR near the stop codon: recruits the catalytic core components METTL3 and METTL14, thereby guiding m6A methylation at specific sites (PubMed:29507755). Required for mRNA polyadenylation via its role in selective m6A methylation: m6A methylation of mRNAs in the 3' UTR near the stop codon correlating with alternative polyadenylation (APA) (PubMed:29507755).[UniProtKB/Swiss-Prot Function]
Locus ID	25962
MW	6.8

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