SIGIRR (NM_021805) Human 3' UTR Clone
CAT#: SC202189
3' UTR clone of single immunoglobulin and toll-interleukin 1 receptor (TIR) domain (SIGIRR) transcript variant 3 for miRNA target validation
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CNY 4,845.00
货期*
3周
规格
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经常一起买 (2)
Specifications
Product Data | |
Product Name | SIGIRR (NM_021805) Human 3' UTR Clone |
Vector | pMirTarget |
Synonyms | IL-1R8; TIR8 |
ACCN | NM_021805 |
Insert Size | 210 bp |
Sequence Data |
>SC202189 3’UTR clone of NM_021805
The sequence shown below is from the reference sequence of NM_021805. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC TACTGCCTGGTGTCCAAGGATGATATGTAGCTCCCACCCCAGAGTGCAGGATCATAGGGACAGCGGGGG CCAGGGCAGCGGCGTCGCTCCTCTGCTCAACAGGACCACAACCCCTGCCAGCAGCCCTGGGACCCTGCC AGCAGCCCTGGGAAAAGGCTGTGGCCTCAGGGCGCCTCCCAGTGCCAGAAAATAAAGTCCTTTTGGATT CTG ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG |
Restriction Sites | SgfI-MluI |
OTI Disclaimer | Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs). |
Reference Data | |
RefSeq | NM_021805.3 |
Synonyms | IL-1R8; TIR8 |
Summary | Acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through an TIR-TIR domain interaction with TLR4. Through its extracellular domain interferes with the heterodimerization of Il1R1 and IL1RAP.[UniProtKB/Swiss-Prot Function] |
Locus ID | 59307 |
MW | 7.8 |
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