HLA DM (HLA-DMA) (NM_006120) Human 3' UTR Clone

Specifications

Product Data
Product Name	HLA DM (HLA-DMA) (NM_006120) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	D6S222E; DMA; HLADM; RING6
ACCN	NM_006120
Insert Size	276 bp
Sequence Data	Insert Sequence (showhide) >SC203075 3’UTR clone of NM_006120 The sequence shown below is from the reference sequence of NM_006120. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC TACTTCCGGAAGCCTTGCTCAGGTGACTGATTCTTCCAGACCAGAGTTTGATGCCAGCAGCTTCGGCCA TCCAAACAGAGGATGCTCAGATTTCTCACATCCTGCCCAGGATCTCCTCTTAGGGTAGAAGTCTCTGGG ACATCCCTGGGGTGTGTGTGTAGATTTCCCACCTGGGGACTCTGCTGTCCCTGGGCTTGCATCCCAGGG ATCCCAGAGTGGCCTGCCTATCACAACCACATCCCTTCCCCCCACAAGGCAATAAATCTCATTTCTTTA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_006120.4
Synonyms	D6S222E; DMA; HLADM; RING6
Summary	HLA-DMA belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta chain (DMB), both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail. [provided by RefSeq, Jul 2008]
Locus ID	3108
MW	10.4

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