FHIT (NM_002012) Human 3' UTR Clone

Specifications

Product Data
Product Name	FHIT (NM_002012) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	AP3Aase; FRA3B
ACCN	NM_002012
Insert Size	2000 bp
Sequence Data	Insert Sequence (showhide) >SC203718 3’UTR clone of NM_002012 The sequence shown below is from the reference sequence of NM_002012. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GCCGCAGCTCTGCGGGTCTACTTTCAGTGACACAGATGTTTTTCAGATCCTGAATTCCAGCAAAAGAGC TATTGCCAACCAGTTTGAAGACCGCCCCCCGCCTCTCCCCAAGAGGAACTGAATCAGCATGAAAATGCA GTTTCTTCATCTCACCATCCTGTATTCTTCAACCAGTGATCCCCCACCTCGGTCACTCCAACTCCCTTA AAATACCTAGACCTAAACGGCTCAGACAGGCAGATTTGAGGTTTCCCCCTGTCTCCTTATTCGGCAGCC TTATGATTAAACTTCCTTCTCTGCTGCAACCCTGTGTCTCGGTGTATTGACTTGCCATGAATTAGGCAA CAAACCTATTACAGTTACAGTTACTTTTTTAAAGGAAATTCAATCGTTGGATTGGTCCACCTGCTTATT TCTTCCCTTTTCAAAAAAAATGTCTACATATTGAATTTTTATACATTAAGTGGTTCATGAAACCCCTGA AATGTGTTAGTAAATAGGGCAATTATGAAATATTTGGACATAGCTAGACTTTAAAAATTGTTAATCTGA AGGTCAGATAGACTTGGCCTTCTCCAGCTTTCGTGATTATTCCCTCAGCAGCAAGCTAGTCTTAGGCAG AGCAAGTTTAAAGACATTCATGGTGCTCACTCTGCAAAACTGCACAATTCTCAACATGCACAGAGGCAG ACATGATAGGGCTCAGCCCTGGAATTGATAACACTAGCCAACACACTTGCTAAGAATTTATAAGATGTA GACCCTGTTATTATCCTGTCTTGCAAGTGATGAGAAAACTAAGGCTTAAGGATGTTAAGTATTATTAGT TCAAGGCCAACGGTAAGTGGCAAAGCTCAGATTTGAATCCAGGCAGTCCCACCCTAAAGGCCATTCTCT TAGTCTGTGTACTGCCCTCCTTGCTAAAAGAGCTCACCTCTCTAGCCACTTCCTTCTCCCTGTCCCATC TCCCCTTGTACCCTCCAAATAGTCTTCTTAGCCTCTTCACCTTATCTACTGGCCTATTTCTGCCTTGAG GACCTCCCACCTCCTCGCCTGCTGGACTTCTTCCTTACCTGCCTTGTTAATACAACCCTGCCCAGCACC TGCCTCCCTGGTCACACTACAGCCAGGTAGCAGAAACCAAAATGGGCCTGGATTTCCCCAACCAACTTG GTTCTACTTGCAAGATTCTCAGATCATGCTGAATCCTGCCTAGGCTACCCTCCCACTTTCTTTTCTTTA CCATCTGACCACATGCCTAAATAAACATCACTTGGGCGAATACAGTGTTCCCCAAATTGCATTCATTCC CATTTTGTCATGATTTTTCTTATCTTTGTGGACCACCTAGAGCATTATTTACTTGATTCACTTTTTGAA TTTTAGTATATATATCTTAAACTTTATATTTCAGCCTCAAAGAAAAACAAGTACTACCTGTAATTAGAA GTTAAGCATAAAAATAAACATAAGAGAAAAACAATGCTGATGATTTCCAGCTCTGCATAGTTGCTTGCC TTAGCAACTAGGAGTGAGATTCAGTCTCTGTGTTAAAAAGTGAGGCTAGCCACCATTAGAGGGGCATTT AATTCTAGCACCAAACCGAAACTCTCCATTTGGCATATTCAGAAGGATTAAAGAGAATAACCTACTGAG AGATTCAATGTAGATCACTTAAGATTATCTTAAACAGGAATATGACTGACTCCCAACTTTGGAGAAACA GCAGTGGAGGCCAGATCTTAAACCCAGAGCAAGCTGGCTTTAGACTTGCTTCAACCCTAAACCAGTACT CCTTTCCACCCACCCACCTCCCCCCAACCCCTGCAGGCATATCAAGAAGACAAGGTGCATGGGGGAAAA CCAAAGAGTCAGCTTCCCTAGGGCTGATGGGTCAAATCTCAGTGCTTGCCTCTGACATTTTGCTTGCCG ACAGTCTGTCTTGAAAACCAACAGGTTGCAAAGAAGAATGTGAACACCTATATCCAGAGATGCCCTAT ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_002012.4
Synonyms	AP3Aase; FRA3B
Summary	The protein encoded by this gene is a P1-P3-bis(5'-adenosyl) triphosphate hydrolase involved in purine metabolism. This gene encompasses the common fragile site FRA3B on chromosome 3, where carcinogen-induced damage can lead to translocations and aberrant transcripts. In fact, aberrant transcripts from this gene have been found in about half of all esophageal, stomach, and colon carcinomas. The encoded protein is also a tumor suppressor, as loss of its activity results in replication stress and DNA damage. [provided by RefSeq, Aug 2017]
Locus ID	2272
MW	75.2

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