DAD1 (NM_001344) Human 3' UTR Clone

Specifications

Product Data
Product Name	DAD1 (NM_001344) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	OST2
ACCN	NM_001344
Insert Size	305 bp
Sequence Data	Insert Sequence (showhide) >SC203745 3’UTR clone of NM_001344 The sequence shown below is from the reference sequence of NM_001344. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CACCTTGTTGTCATGAACTTTGTTGGCTGAATCATTCTCATTTACTTAATTGAGGAGTAGGAGACTAAA AGAATGTTCACTCTTTGAATTTCCTGGATAAGAGTTCTGGAGATGGCAGCTTATTGGACACATGGATTT TCTTCAGATTTGCACTTACTGCTAGCTCTGCTTTTTATGCAGGAGAAAAGCCCAGAGTTCACTGTGTGT CAGAACAACTTTCTAACAAACATTTATTAATCCAGCCTCTGCCTTTCATTAAATGTAACCTTTTGCCTT CCAAATTAAAGAACTCCATGCCACTCCTC ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_001344.4
Synonyms	OST2
Summary	DAD1, the defender against apoptotic cell death, was initially identified as a negative regulator of programmed cell death in the temperature sensitive tsBN7 cell line. The DAD1 protein disappeared in temperature-sensitive cells following a shift to the nonpermissive temperature, suggesting that loss of the DAD1 protein triggered apoptosis. DAD1 is believed to be a tightly associated subunit of oligosaccharyltransferase both in the intact membrane and in the purified enzyme, thus reflecting the essential nature of N-linked glycosylation in eukaryotes. [provided by RefSeq, Jul 2008]
Locus ID	1603
MW	11.8

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