HLA-DRB4 (NM_021983) Human 3' UTR Clone

Specifications

Product Data
Product Name	HLA-DRB4 (NM_021983) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	DR4; DRB4; HLA-DR4B; HLA-DRB4*
ACCN	NM_021983
Insert Size	351 bp
Sequence Data	Insert Sequence (showhide) >SC204248 3’UTR clone of NM_021983 The sequence shown below is from the reference sequence of NM_021983. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GGACTTCAGCCAACAGGACTCTTGAGCTGAAGTGCAGATGACCACATTCAAGGAAGAACCTTCTGCCCC AGCTTTGCAAGATGAAAAGCTTTCCCACTTGGCTCTTATTCTTCCACAAGAGCTTTGTCAGGACCAGGT TGTTACTGGTTCAGCAACTCTGCAGAAAATGTCCTCCCTTGTGGCTTCCTTAGCTCCTGTTCTTGGCCT GAAGCCTCACAGCTTTGATGGCAGTGCCTCATCTTCAACTTTTGTGCTTCCCTTTACCTAAACTGTCCT GCCTCCCGTGCATCTGTACTCCCCTTGTGCCACACATTGCATTATTAAATGTTTCTCAAACATGGAGTT AAAAAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_021983.4
Synonyms	DR4; DRB4; HLA-DR4B; HLA-DRB4*
Summary	HLA-DRB4 belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DRA) and a beta (DRB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells. The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DR molecule the beta chain contains all the polymorphisms specifying the peptide binding specificities. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. There are multiple pseudogenes of this gene. [provided by RefSeq, Feb 2020]
Locus ID	3126
MW	12.9

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