APEX2 (NM_014481) Human 3' UTR Clone

Specifications

Product Data
Product Name	APEX2 (NM_014481) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	APE2; APEXL2; XTH2; ZGRF2
ACCN	NM_014481
Insert Size	1652 bp
Sequence Data	Insert Sequence (showhide) >SC204804 3’UTR clone of NM_014481 The sequence shown below is from the reference sequence of NM_014481. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC AACTTCTTCCTCTGGAGCAGGCCCAGCTGAACCAATGGAGGCCTGGGGACATCTGGCATGGTCACCCCT GCACATGATCTGAGGCCAGCTCCCCTTCCCTGAGCTGCCTCCTGCTTCTCCCTCAAAGTCTCCTACCCT TCTCTTCCTCTTTTAAGCCCTCTCTTCCTCGCTTTCCTTCCTACCTAGCTCCTTGTTGGTGAGCTTCTT GTGCCTTAATCCTGTGACCCAGCCCCTTACACCACTTTCCACCTTCCTGTCCGAAGTACACGGACACTA GCTGCCCCAGGAAGTTGTGTGATTTTAAATCACTTCTGTCTTTGCTGGAAAGTGTATTTGTGCATAAAT AAAGTCTGTGTATTTGTTTCAGGGTTGCACTTTGGACATTGTGGAGGTACTCCATAAAGTTGAGTCAGA GAAGCTATCTCAATACTTGGTTTGCCGGCTGGCTGTAGCCCAATGATGTAATTCCCAGAGAAAGGGGAG GAGGGAGGGGGGAGGAGGGAATAGTGAGGCGTGAGCAGCAGTGCTCACCATAAAGGGTTCTCTGCTCAG TTGTAGGAATTTCCTGTACGGCTAAGGTGAAATCAGCAAGGAAGGTGGGCTGTGTAGCCTTAAACCAGA GCTTTCCAGCTAGTGCGTCCCACAGCTGCCACAGTGGGTTACAGGGTTGAAAGAAACGGTCCTCAGCCC TCAGAGTTGCCAGGCAGGGCCTGGGACCACACAAGTTTCAGGGACGATTGCCTCCTTAGCAAGTAGTAT CATTAGTACCCCTAAGTGTGCCATGGAAATGTTTCCTGTATACTGTGACCTGGAAAGTGGGAGCATTGC TTTGAACACAGTGCTTGCTCTAGCCAAGCCTCTTCTCACCTTTGAAAATGGGACTGGTAGACCAGGCAC AGTGGTGCACGCCTGTAATCCCAGCACTTTGGGAGGCTGAGATGGGTGGATCACCTGAGGTCAGGAGTT CGCAACCAGCCTAACATGGTGAGACCCCGTCTCTACTAAATACAAAAAAATTAACTGGGCGTGGTGGCG CGTGCCTGTAATCCAAGCTACTTAGGAGGCTGAGACAGGAGAATAGCTTGTACCTGGGAGGCGGAGGTT GCAGTGGGCTGAGATCATGCATTGCACTCCAGCCTGGGCAACAAGAGTGAAATTCAGTCTCCAAAAAAA AAAAAAGAAAAGAAAAAGAATGGGACTGGTAAATCCTGTTCTGTGGGATGCCGTGGGAGGGAGAGAGGA TAATGGATTGAGGAAGACATCCATATCCCCTTATGGAAAATACCTCTTTGGTTTTGGGGAACCACTCCT TTCTAGGGAATTTGGTTAGGGCTGACTCATTTCCTGGCTTCAGGGGCTACCCTGGGCCCAGATTTCCAG GGCCCGGATTACCAGTGAAGCGTCAATCCCTGGATTTTTATTGAAACCATTGGAGAAGAGCCATCTCAA ATAAATCTGCCAAGTATCCTAGCTCTTTGCAACTCACTGTGTAGTTTTTGGGCATTTCCTTCCTCTTTC TCATTCTGTTTCCCTGTTGGTAAAATGGAATGGTGACCAACAAGTGACCTATGGTTACCTCATAGATCT GCCACTTGTCTGAGGGAGTCAGAATGCACTTGTCTGTTCCCTGTCCAATAAAAGGCTTCACATGC ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_014481.4
Synonyms	APE2; APEXL2; XTH2; ZGRF2
Summary	Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes a protein shown to have a weak class II AP endonuclease activity. Most of the encoded protein is located in the nucleus but some is also present in mitochondria. This protein may play an important role in both nuclear and mitochondrial base excision repair. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2012]
Locus ID	27301
MW	61.2

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