CCM2 (NM_031443) Human 3' UTR Clone

CAT#: SC205724

3' UTR clone of cerebral cavernous malformation 2 (CCM2) transcript variant 2 for miRNA target validation



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CNY 4,845.00


货期*
3周

规格
    • 10 ug

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经常一起买 (2)
Firefly luciferase assay kit, 150 assays
    • 1 kit

CNY 1,520.00


DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
    • 5 x 200 ul

CNY 1,280.00

Specifications

Product Data
Product Name CCM2 (NM_031443) Human 3' UTR Clone
Vector pMirTarget
Synonyms C7orf22; OSM; PP10187
ACCN NM_031443
Insert Size 426 bp
Sequence Data
>SC205724 3’UTR clone of NM_031443
The sequence shown below is from the reference sequence of NM_031443. The complete sequence of this clone may contain minor differences, such as SNPs.
Blue=Stop Codon Red=Cloning site

GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG
TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC
GGCTGCAGCATGGACCAGGACTCAGCATGATGGACAGTGGATGGGGGGGCACCCACACCTTCCGCGCAG
TCGTCATAGGCCTTCCCAGAAGGAGCTGCCCAGACCTGCGTGTCAGCCCTTGGTGGTGGCCAGGGAGAG
GCGCCCGGTGCAGATGGCCCCGGGCGGCCCAGGTCCTCTACTGTGAAGGAGCAGGGAGCTGCCGAGGGA
CACGAGCCTCAGTGCGGGGTGGAAGGCTCTTTGCCTTGTCCACCAGGGCTCAGCCAAGCCCTGCAGTGT
GTCCCCGCTCGGGGAGGGCCCGGCCGAGCGGGCAGGGAGAGCCAGTCCTGTCGGCTGGGCCCTTGGACG
GCTGTCAGTTTTGCACATGATGTTCCTATTGTAACTCTCAGAGACCTTAAAAAGAAGTTTACTGCAATG
TGAATAATTTAA
ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA
CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites SgfI-MluI     
OTI Disclaimer Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq NM_031443.4
Synonyms C7orf22; OSM; PP10187
Summary This gene encodes a scaffold protein that functions in the stress-activated p38 Mitogen-activated protein kinase (MAPK) signaling cascade. The protein interacts with SMAD specific E3 ubiquitin protein ligase 1 (also known as SMURF1) via a phosphotyrosine binding domain to promote RhoA degradation. The protein is required for normal cytoskeletal structure, cell-cell interactions, and lumen formation in endothelial cells. Mutations in this gene result in cerebral cavernous malformations. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Nov 2009]
Locus ID 83605
MW 14.2
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