SOCS1 (NM_003745) Human 3' UTR Clone

Specifications

Product Data
Product Name	SOCS1 (NM_003745) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	AISIMD; CIS1; CISH1; JAB; SOCS-1; SSI-1; SSI1; TIP-3; TIP3
ACCN	NM_003745
Insert Size	456 bp
Sequence Data	Insert Sequence (showhide) >SC205748 3’UTR clone of NM_003745 The sequence shown below is from the reference sequence of NM_003745. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC TACCTGAGCTCCTTCCCCTTCCAGATTTGACCGGCAGCGCCCGCCGTGCACGCAGCATTAACTGGGATG CCGTGTTATTTTGTTATTACTTGCCTGGAACCATGTGGGTACCCTCCCCGGCCTGGGTTGGAGGGAGCG GATGGGTGTAGGGGCGAGGCGCCTCCCGCCCTCGGCTGGAGACGAGGCCGCAGACCCCTTCTCACCTCT TGAGGGGGTCCTCCCCCTCCTGGTGCTCCCTCTGGGTCCCCCTGGTTGTTGTAGCAGCTTAACTGTATC TGGAGCCAGGACCTGAACTCGCACCTCCTACCTCTTCATGTTTACATATACCCAGTATCTTTGCACAAA CCAGGGGTTGGGGGAGGGTCTCTGGCTTTATTTTTCTGCTGTGCAGAATCCTATTTTATATTTTTTAAA GTCAGTTTAGGTAATAAACTTTATTATGAAAGTTTTTTTTTT ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_003745.2
Synonyms	AISIMD; CIS1; CISH1; JAB; SOCS-1; SSI-1; SSI1; TIP-3; TIP3
Summary	This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival. [provided by RefSeq, Jul 2008]
Locus ID	8651
MW	16.5

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