TGIF (TGIF1) (NM_003244) Human 3' UTR Clone

Specifications

Product Data
Product Name	TGIF (TGIF1) (NM_003244) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	HPE4; TGIF
ACCN	NM_003244
Insert Size	2000 bp
Sequence Data	Insert Sequence (showhide) >SC206531 3’UTR clone of NM_003244 The sequence shown below is from the reference sequence of NM_003244. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC ATGGAGCTTCAGGCAAAACTTACAGCTTAACCCATTTTCAAGCAAAACAGTTCTCAGAAATGTCATGAT TGCCGGGGTGAAGGCAAGAGATGAATTGCATTATTTTATATATTTTTTATTAATATTTGCACATGGGAT TGCTAAAACAGCTTCCTGTTACTGAGATGTCTTCAATGGAATACAGTCATTCCAAGAACTATAAACTTA AAGCTACTGTAGAAACAAAGGGTTTTCTTTTTTAAATGTTTCTTGGTAGATTATTCATAATGTGAGATG GTTCCCAATATCATGTGATTTTTTTTTTCCTCCCCTTCCCTTTTTTTGTTATTTTTTCAGACTGTGCAA TACTTAGAGAACCTATAGCATCTTCTCATTCCCATGTGGAACAGGATGCCCACATACTGTCTAATTAAT AAATTTTCCATTTTTTTTCAAACAAGTATGAATCTAGTTGGTTGATGCCTTTTTTTTCATGACATAATA AAGTATTTTCTTTAAAAATTGTTGTAATTCAGAGTATTTCTGTTGAGGGAGGTGCTTCTTAAAAATAAG TAGGAATATAGCACCCCAGTGAGCAGGAAGCTGGGGGGGTAGGGTGCAGTGTTAGGGGGTGTCACCAGC TCTTTGAAAACCTGTGGACAACAAGCCAGTTTGCATAAACAGGATGTGTGATATTTACTCTTGATAGGA GGCATAGCAGGCCCTTAGAGCTTTACTTAAACTGCATGGCAAATTGAAATGAATCATTTTAGTGTTTAG CTAGCCACTAAATCCCTTGCTGATCTGTCCTGCGTAGTTTAAAACGTGGCCATGTTATAAAGAAAAGTC TTGAAGCATCCGGTTATTGCTGAGTTTTCAGAAGAAAACAACGCAAGCAATCTCTTGCCCTTTTTCCAC GTTACCCTTTAAAATAACCTTTGTTCAGTGGTACATTTAGTTAAGGCATTTGTATTCAAATGTAGCATA GTATTTGCAGAGAAATTACCTTTTAAAACATCTCAAAAGTGTTTTCTAAAATGATGAAATAAACGGTGG GGTTCTGTCTATGGTGGGATTGTCAGTTTATTAGGTGAGTATTTTCCAAGGTCTCAGTTTGTGAAAAAA TGGTGCTATGTACAAGTGGAGTTTGTTGGGATAGACAATCACTTACAAAGCCCAGATGGCCAGAAGGGA ATTGGTGTTGCTCCTTTCACTTGTATGGTTGAGCAGATTTGTCACATGCCACAAAACCATTCTTTGTAG TCATGCTTAGTATGAGCTTGCTTTGTTGTTACGGTCATGTTCTTTCCAGCCCTGCCCCAGCTATGAATT GTCTAAGTGTGAGGGAGCATCAGAGCTTCAGTATTGTTTAAAGAATGTAGAAAAATACAAATTTGTCTA ATTTTGAAACTATTTTAGAAAGTCCCTACTGTAGAAAGAGCTAAACTCAAAGACTTTCCTTGTAAGTGA AAGAAAAAAACTGCTGATGATTACCAAGAGGCGTAAGAAAATTAGGTGAGGGAATGTTGTGCTCTAGCC TGTGGGGTGCAGCTTCGTAGGGCACATCAGCTTAGAATGGTCTGGCCTCACCTCAGAGAGTCACAGAAA TAGACAAAAACCCAAAAAGTACTAGTAAAGTAAATACAAGGAACAAAATAAACATTAATAAAAATGAAT GACGCAAAGGTGATCCAGAATCATTACTTGCTCCAACAGCTAGATCAAAGGCTGAACATTTTGCTTTAG TATAGATGAGGGAAATGAGCAAGTCCTAAAAGGTTTGCCCTGTTACGGTGTTTCATCACTCATACTGGA AGGAGAAGGAAAGGAGCCATATGACTCATTTAAAAGAAAAACTGTAAGTCACCTTAAATTCCCTATGTT TTACTTCATTTTTTCCCTATTGAGGTTGTTACAGGTCATGGTTGATAATAGTTGGTGTTGAATGAATGT AATCCATTATTTAAAAACAGGTACATTTAAGTGAAAAGATAAATGTAAAAAGCTGTTCATATCAAAGC ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_003244.4
Synonyms	HPE4; TGIF
Summary	The protein encoded by this gene is a member of the three-amino acid loop extension (TALE) superclass of atypical homeodomains. TALE homeobox proteins are highly conserved transcription regulators. This particular homeodomain binds to a previously characterized retinoid X receptor responsive element from the cellular retinol-binding protein II promoter. In addition to its role in inhibiting 9-cis-retinoic acid-dependent RXR alpha transcription activation of the retinoic acid responsive element, the protein is an active transcriptional co-repressor of SMAD2 and may participate in the transmission of nuclear signals during development and in the adult. Mutations in this gene are associated with holoprosencephaly type 4, which is a structural anomaly of the brain. Alternative splicing has been observed at this locus and multiple splice variants encoding distinct isoforms are described. [provided by RefSeq, Jul 2013]
Locus ID	7050
MW	76.7

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