Cathepsin F (CTSF) (NM_003793) Human 3' UTR Clone

Specifications

Product Data
Product Name	Cathepsin F (CTSF) (NM_003793) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	CATSF; CLN13
ACCN	NM_003793
Insert Size	499 bp
Sequence Data	Insert Sequence (showhide) >SC206576 3’UTR clone of NM_003793 The sequence shown below is from the reference sequence of NM_003793. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC ACCATGGCCAGCTCGGCGGTGGTGGACTGAAGAGGGGCCCCCAGCTCGGGACCTGGTGCTGATCAGAGT GGCTGCTGCCCCAGCCTGACATGTGTCCAGGCCCCTCCCCGGGAGGTACAGCTGGCAGAGGGAAAGGCA CTGGGTACCTCAGGGTGAGCAGAGGGCACTGGGCTGGGGCACAGCCCCTGCTTCCCTGCACCCCATTCC CACCCTGAAGTTCTGCACCTGCACCTTTGTTGAATTGTGGTAGCTTAGGAGGATGTCGGGGTGAAGGGT GGTATCTTGGCAGTTGAAGCTGGGGCAAGAACTCTGGGCTTGGGTAATGAGCAGGAAGAAAATTTTCTG ATCTTAAGCCCAGCTCTGTTCTGCCCCCGCTTTCCTCTGTTTGATACTATAAATTTTCTGGTTCCCTTG GATTTAGGGATAGTGTCCCTCTCCATGTCCAGGAAACTTGTAACCACCCTTTTCTAACAGCAATAAAGA GGTGTCCTTGTCCCGA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_003793.4
Synonyms	CATSF; CLN13
Summary	Cathepsins are papain family cysteine proteinases that represent a major component of the lysosomal proteolytic system. Cathepsins generally contain a signal sequence, followed by a propeptide and then a catalytically active mature region. The very long (251 amino acid residues) proregion of the cathepsin F precursor contains a C-terminal domain similar to the pro-segment of cathepsin L-like enzymes, a 50-residue flexible linker peptide, and an N-terminal domain predicted to adopt a cystatin-like fold. The cathepsin F proregion is unique within the papain family cysteine proteases in that it contains this additional N-terminal segment predicted to share structural similarities with cysteine protease inhibitors of the cystatin superfamily. This cystatin-like domain contains some of the elements known to be important for inhibitory activity. CTSF encodes a predicted protein of 484 amino acids which contains a 19 residue signal peptide. Cathepsin F contains five potential N-glycosylation sites, and it may be targeted to the endosomal/lysosomal compartment via the mannose 6-phosphate receptor pathway. The cathepsin F gene is ubiquitously expressed, and it maps to chromosome 11q13, close to the gene encoding cathepsin W. [provided by RefSeq, Jul 2008]
Locus ID	8722
MW	17.3

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