GABARAPL2 (NM_007285) Human 3' UTR Clone

Specifications

Product Data
Product Name	GABARAPL2 (NM_007285) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	ATG8; ATG8C; GATE-16; GATE16; GEF-2; GEF2
ACCN	NM_007285
Insert Size	542 bp
Sequence Data	Insert Sequence (showhide) >SC207260 3’UTR clone of NM_007285 The sequence shown below is from the reference sequence of NM_007285. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC TACAGCGGAGAGAACACTTTTGGCTTCTGAGGGCCATTGCTGGGCTAGGTGCACCGTAACTGCTTGTGT ATCTTGTAAATAGCCAGCCATTTTCAGTTATTATACCAGAACCTCTTCACATAGACCTATTAGTGCATT TGTAACTGGATTTATTTCTTAATATATTGGAAGGTTTTGTTTCCTTAGACTAGTAAATTATCATACAGA GTTTTATTTTGAGTTTTTCTTTTTGTGCATTGTCCTCATGCCTGTATTCTCCAGGAAACTTGTCCTTCT GGAAATCATATTGAATGATATTTCTATATCGAAGTGAGGTAGGTGCGGTATTAAAGTGAAAGGGAAGGT GATGCATTTATTCTGGGTTATGCTTGAAGTGTTAGATGGCTAAGTATTAAAATTATCCAAATTAAATCC TTAGCAGTCAGAACACTTGCTTCACTAGAATATGCCAACTGCCAATCATGTTGGACTGAGCTAATTTGT TCCTCTTTCTGAAACTATTAAGGTAAATAATTAACAATAAAAATTCTCTTATAAAGGCA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_007285.7
Synonyms	ATG8; ATG8C; GATE-16; GATE16; GEF-2; GEF2
Summary	Ubiquitin-like modifier involved in intra-Golgi traffic. Modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1 (By similarity). Involved in autophagy. Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation.[UniProtKB/Swiss-Prot Function]
Locus ID	11345
MW	21.1

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