RGR (NM_002921) Human 3' UTR Clone

Specifications

Product Data
Product Name	RGR (NM_002921) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	RP44
ACCN	NM_002921
Insert Size	1351 bp
Sequence Data	Insert Sequence (showhide) >SC207359 3’UTR clone of NM_002921 The sequence shown below is from the reference sequence of NM_002921. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CAGAAGAGGGAGAAGGACCGAACCAAGTGAGCCTGCCACCCTGGAGTGAGCCCCAGGCCAGGAGGCTGT TCCAGGAGTCCTGCCCAGCAGCCTCAGTGGCCAAGCCCAGACACTCACCCACCTTCCCCAGTGGCCCCG TGGATCCTGGTCCTAGGCTGGACACAGGATTCAGAAAGACACCAGGCTGCACAGAAAGAGCCAGATGGA CCTGAGTGTCGGTCACAGCCCCCTACACTCAAGGCTGAGAGGCCTCAGGAAAGTCATTCCTTTTTAAAA ATAATAATAAATGTAAGGGGGTACAGTGCAGTTTTGTTACATGGATAGATTGCCTAGTGGTGAAGTCTG GGCTTTTAGTGTAACCATCACCCTAATAATATACGTTGTACCCATTAAGTTATTTCTCATCCCTCACCC CCTCCCACCTTGTCACCCTTCTGAGTCTCCAATGTCTATTATTCCACACTCCATGTCCACGTGTACACA TTATTTAGCTCCCACTTACAAGTGAGAACATGTGGTATTTGACTTTCTGTTTTTGAGTTATTTCACTTA AAATAATGACCTCCAGTTTCATCCATGTTGCTGCAAAAGACATGATCTCGTTCTTTTTTATGGCAGTGT AGTATTCCATTCCATATACATATATAAACGTTATATATATGTAACGTTTTCTTTATCCAATCATCTGTT GATGGATAGATTCCATATCTTTGCTACTGTAAACAGCTGTGATAAGCATACAAGTGCAGGTTTCTTTTT GATATACTGATTTCTTTTCCTTTGGGTAGATACCAGTAGTAGGACTGCTGGATCAAATGGTAGCTCTAT TTTTAAGACAGTATGGAGAAATCACCATACTGTTTTCCATAGGGGTTGTACTAATTTACAGTCCCACCA ACAGTGTATAGGTGTTCCCTTTTCTCTGCATCCTTACCAATATCTGTAATTTTTTGACTTTTTAATAAT AGCCATTCTCACTTGTGTGAGATAAGGTCTCATTGTGGTTTTAATTTCCATTTCTCTGATGACTTTTGA TGTTAAGCATTTTTTCATATGCTTCTTAGCCACGTGTATGTATTCTTTTTGAAAAAATGTTTATTCATG TCTTTTGCCCACTTTTTAATGGCATTATTTGGATTTTTTTTGTTGAGTTATTTGAGTTTCTTATATATT CTGGATAATAGTCTGGATAATATATTCTGGATAATATATAATAGTCTTATATATTCTGGATATATTCTG GATACATGGTTTGCAAATATTTTCTCCGGTTCTGCACGTTGTTCATTCTGTTGATGGTTTATTTTGCTG TGCAGAAACTTTTTTAGTTTAATTAAGTCCCATTTGTCTA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_002921.4
Synonyms	RP44
Summary	This gene encodes a putative retinal G-protein coupled receptor. The gene is a member of the opsin subfamily of the 7 transmembrane, G-protein coupled receptor 1 family. Like other opsins which bind retinaldehyde, it contains a conserved lysine residue in the seventh transmembrane domain. The protein acts as a photoisomerase to catalyze the conversion of all-trans-retinal to 11-cis-retinal. The reverse isomerization occurs with rhodopsin in retinal photoreceptor cells. The protein is exclusively expressed in tissue adjacent to retinal photoreceptor cells, the retinal pigment epithelium and Mueller cells. This gene may be associated with autosomal recessive and autosomal dominant retinitis pigmentosa (arRP and adRP, respectively). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Locus ID	5995
MW	52.2

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