GAD65 (GAD2) (NM_000818) Human 3' UTR Clone
CAT#: SC207536
3' UTR clone of glutamate decarboxylase 2 (pancreatic islets and brain 65kDa) (GAD2) transcript variant 1 for miRNA target validation
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CNY 4,845.00
货期*
3周
规格
Cited in 4 publications. |
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经常一起买 (2)
Specifications
Product Data | |
Product Name | GAD65 (GAD2) (NM_000818) Human 3' UTR Clone |
Vector | pMirTarget |
Synonyms | GAD65 |
ACCN | NM_000818 |
Insert Size | 589 bp |
Sequence Data |
>SC207536 3’UTR clone of NM_000818
The sequence shown below is from the reference sequence of NM_000818. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GAAATAGAACGCCTTGGACAAGATTTATAATAACCTTGCTCACCAAGCTGTTCCACTTCTCTAGAGAAC ATGCCCTCAGCTAAGCCCCCTACTGAGAAACTTCCTTTGAGAATTGTGCGACTTCACAAAATGCAAGGT GAACACCACTTTGTCTCTGAGAACAGACGTTACCAATTATGGAGTGTCACCAGCTGCCAAAATCGTAGG TGTTGGCTCTGCTGGTCACTGGAGTAGTTGCTACTCTTCAGAATATGGACAAAGAAGGCACAGGTGTAA ATATAGTAGCAGGATGAGGAACCTCAAACTGGGTATCATTTTGCACGTGCTCTTCTGTTCTCAAATGCT AAATGCAAACACTGTGTATTTATTAGTTAGGTGTGCCAAACTACCGTTCCCAAATTGGTGTTTCTGAAT GACATCAACATTCCCCCAACATTACTCCATTACTAAAGACAGAAAAAAATAAAAACATAAAATATACAA ACATGTGGCAACCTGTTCTTCCTACCAAATATAAACTTGTGTATGATCCAAGTATTTTATCTGTGTTGT CTCTCTAAACCCAAATAAATGTGTAAATGTGGACACA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG |
Restriction Sites | SgfI-MluI |
OTI Disclaimer | Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs). |
Reference Data | |
RefSeq | NM_000818.3 |
Synonyms | GAD65 |
Summary | This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2008] |
Locus ID | 2572 |
MW | 22.9 |
Citations (4)
The use of this cDNA Clones has been cited in the following citations: |
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Abundant glutamic acid decarboxylase (GAD)-reactive B cells in gad-antibody-associated neurological disorders.
,null,
Annals of neurology
,PubMed ID 30635933
[GAD2]
|
Cerebellar Ataxia and Glutamic Acid Decarboxylase Antibodies
,null,
JAMA neurology
,PubMed ID 24934144
[GAD2]
|
Transglutaminase 4 as a prostate autoantigen in male subfertility.
,null,
Science translational medicine
,PubMed ID 26084804
[GAD2]
|
Palmitoyl protein thioesterase-1 deficiency impairs synaptic vesicle recycling at nerve terminals, contributing to neuropathology in humans and mice
,null,
,PubMed ID 18704195
[GAD2]
|
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