MLKL (NM_152649) Human 3' UTR Clone

CAT#: SC208650

3' UTR clone of mixed lineage kinase domain-like (MLKL) transcript variant 1 for miRNA target validation



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CNY 4,845.00


货期*
3周

规格
    • 10 ug

Product images

经常一起买 (2)
Firefly luciferase assay kit, 150 assays
    • 1 kit

CNY 1,520.00


DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
    • 5 x 200 ul

CNY 1,280.00

Specifications

Product Data
Product Name MLKL (NM_152649) Human 3' UTR Clone
Vector pMirTarget
Synonyms hMLKL
ACCN NM_152649
Insert Size 679 bp
Sequence Data
>SC208650 3’UTR clone of NM_152649
The sequence shown below is from the reference sequence of NM_152649. The complete sequence of this clone may contain minor differences, such as SNPs.
Blue=Stop Codon Red=Cloning site

GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG
TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC
TTAAAGAAACTCTCCACCTTTTCTAAGTAGTGTATCAAAATCTAAACCAAGGAGTCTCTGGACAAGAAG
CTGGGAGAGGCACAAACTGGACATCTCTCTCTCTCATATCCTTCGGCATTGGGTTATCTATGGGTGCAA
GGAGTGGGCACGCTTCTCTGTTACAAATAGAAAACGATTCCAGTCATACAGGACACATCCCACTCCAAA
TGATATTTCCAAAAACATACCTCTGACAGTAACTTTGATAGATGGTTTGTCAAATGTATCTTTCTGGGT
ATCCACACCTCTTGGCAATGAAATTTGCAGCTCCTCCCTTCCATAAATGAAGTCTCTTTCCCCACCATT
TGAATCTGGGCTGGCACTGTGACTTGATTTGATCAATAGAATGTGGAAGAAGTGACTGTATGCCAGTTC
CAAGCCTAGGTTTCAAGAGGCCTTATAAATGTCTGTTGGAACCTTACCCAGCCATGAACATGTTGAGTG
AGCATGCTGGAGAATGAGAGACCACATGAAGCAGAAACATGCTTTCCTAGCTGAAGTCATACTAGCCCA
ACCAACATGGCAGCTAACACATGAATGAGGCCAATCAAGACCAGAAGAACCACTCAAGCAGATCCCAGC
CCAAATTGCCCATTCACACAATCAGGAGCTAAATAAATTACTGTTGTCTTAACACTAA
ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA
CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites SgfI-MluI     
OTI Disclaimer Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq NM_152649.4
Synonyms hMLKL
Summary This gene belongs to the protein kinase superfamily. The encoded protein contains a protein kinase-like domain; however, is thought to be inactive because it lacks several residues required for activity. This protein plays a critical role in tumor necrosis factor (TNF)-induced necroptosis, a programmed cell death process, via interaction with receptor-interacting protein 3 (RIP3), which is a key signaling molecule in necroptosis pathway. Inhibitor studies and knockdown of this gene inhibited TNF-induced necrosis. High levels of this protein and RIP3 are associated with inflammatory bowel disease in children. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Sep 2015]
Locus ID 197259
MW 25.4
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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