IL12RB1 (NM_153701) Human 3' UTR Clone

Specifications

Product Data
Product Name	IL12RB1 (NM_153701) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	CD212; IL-12R-BETA1; IL12RB; IMD30
ACCN	NM_153701
Insert Size	680 bp
Sequence Data	Insert Sequence (showhide) >SC208722 3’UTR clone of NM_153701 The sequence shown below is from the reference sequence of NM_153701. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CACCATACCCGGCTAATTTTGTATTTTTAGTAGAGACGGGGTTTCACCACGTTGGCCAGGCTGGTCTCG AACTCCTGACCTCAAGTGATCCACCTGCCTTGGCCTCCCAAAGTGTTGGGATTATAGGCGTGAGCCACC ATGCCCAGCCTAATTTTTGTATTTTTAGTAGAGATGGAGTTTCACCATGTTGCCCAGGCTGGTCTCAAA CTCCTGCCCTCAGGTGATCCACCCACCTCAGCCTCTCAAAGTGCTGGGATTACAGGTGTGAGCCACTGT GGCCGACCTACTATTTTTATTATTTTTGAGCTAGGTTCTCAGTCTGTTGGCAGACTGGAGTGCAATCAT GGCTCACTGCAGCCTTGAACTCCCAGACTCAAGTGATCCTTCCACCTCAGCCTCTGGAGTAGCTGGGAC TACAGACATGCACCACCACACCTGGTTAATTTTTTATTTTTATTTTTTGTAGAGACAGGTGTCTCTCTA CGTTGCCCAGGCTGGTCTCGAACTCCTGGGCTCAAGTGATCCACCCATCTCCACCTCCCAAAGTGCTAG GATTACAGGCGTGAGCCACCGTACCCAGCCTGGTCCCATATCATAGTGAAATGGTGCCTGTAAAGCTCT CAGCATTGGCTTGGCACATGCAGTTGGTACTCAATAAACGGCTGTTGCTATCCCCAGAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_153701.3
Synonyms	CD212; IL-12R-BETA1; IL12RB; IMD30
Summary	The protein encoded by this gene is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. This protein binds to interleukine 12 (IL12) with a low affinity, and is thought to be a part of IL12 receptor complex. This protein forms a disulfide-linked oligomer, which is required for its IL12 binding activity. The coexpression of this and IL12RB2 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. Mutations in this gene impair the development of interleukin-17-producing T lymphocytes and result in increased susceptibility to mycobacterial and Salmonella infections. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]
Locus ID	3594
MW	25.6

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