WRN (NM_000553) Human 3' UTR Clone

Specifications

Product Data
Product Name	WRN (NM_000553) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	RECQ3; RECQL2; RECQL3
ACCN	NM_000553
Insert Size	2000 bp
Sequence Data	Insert Sequence (showhide) >SC208817 3’UTR clone of NM_000553 The sequence shown below is from the reference sequence of NM_000553. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC AAAACGAAAAGGGGAGGTCTTTTTAGTTAAGCTGGCAATTACCAGAACAATTATGTTTCTTGCTGTATT ATAAGAGGATAGCTATATTTTATTTCTGAAGAGTAAGGAGTAGTATTTTGGCTTAAAAATCATTCTAAT TACAAAGTTCACTGTTTATTGAAGAACTGGCATCTTAAATCAGCCTTCCGCAATTCATGTAGTTTCTGG GTCTTCTGGGAGCCTACGTGAGTACATCACCTAACAGAATATTAAATTAGACTTCCTGTAAGATTGCTT TAAGAAACTGTTACTGTCCTGTTTTCTAATCTCTTTATTAAAACAGTGTATTTGGAAAATGTTATGTGC TCTGATTTGATATAGATAACAGATTAGTAGTTACATGGTAATTATGTGATATAAAATATTCATATATTA TCAAAATTCTGTTTTGTAAATGTAAGAAAGCATAGTTATTTTACAAATTGTTTTTACTGTCTTTTGAAG AAGTTCTTAAATACGTTGTTAAATGGTATTAGTTGACCAGGGCAGTGAAAATGAAACCGCATTTTGGGT GCCATTAAATAGGGAAAAAACATGTAAAAAATGTAAAATGGAGACCAATTGCACTAGGCAAGTGTATAT TTTGTATTTTATATACAATTTCTATTATTTTTCAAGTAATAAAACAATGTTTTTCATACTGAATATTAT ATATATATTTTTTAGCTTTCATTTACTTAATTATTTTAAGTACCTTTATTTTTCCAGGATGTCAGAATT TGATTCTAATCTCTCTTATGTAGCACATGTGACTTAATTTAAAACCTATACTGTGACACAGAGTTGGGT AAACGATGATTATTTAACTTTAAGCAGTTCACCATCCATTTCAAAGCCTTTGATTGGCTTTTTTGTAAA TAAAAATAACTTGTTAAGAAACAAATATATCTGTCATAGAAGAACTAGAAAATCCAGGGAAGTGAGAAA AATGAAAATAAAAATCATTCATAGTTTTACTAGTAGCTAATCACAGTCAACCTCTTTTGTGTATCCCAC CAGACTTTTTTATATTCATTTGTTTTTAGTTAAAATATAAAAGTCTCGTATATTCCCATTTTTCTGCAT TGCATTACCAGAAGGTAGTGGCGCCTATTAAATATGTGATATGTTGTTGTCCAGCCATGGCTTCTGCAT TTGCATGCTTTTGTGTGTGCATCTGCAATACCCTGTGAATATCCTGTGTGATGGAGTGGCAAGTACGCA CAGACACGTCTGCTGCATGCCTAGGTACGAGGCTGTCTCCAGGAGAAGCACTTGTTTGATTATTTGAGT TGCCAATTGAATTTGCTGCTTTTTTTCATGGCTTGCCATTTTCACTGAAAAGAATGACTAATGAAAAAC GATGATTGGTTATTAGATTTGGATGTTTGGCAGACATTTTCTCAAAATTGAACTAAGTTGGCCTCTTCA CGGAAAACAACTGGTATTTGTTGTGCCAATGATAAAATTGGAGATTTCTAGCAAAATGTATAATTTTGG AAAAGTTGTGTTCCTCCACTGGAAGCTTGACAGCTTTCCTTAACATAAAGACTTCTCTTTCTCTTCGCT TTCACTACTACTACTACTAATTCTTCTTCTGATTCTTCTTCTTCTCCTTCTTCCTTCTTCCTTCCTTCC TCCTCCTCCTCCTTCTTCTTCCTCTTCCTCTTCTTCTTTCTCTCTTTCCTTCCTTCCCTTCCCTTCCCC TTCCTTCCTTCCTTCCTTCCTTCCTCCCTCCCTCCCTCCCTCCCTCCCTCCCTCCTTTCTTTTTCTTTC TCTTTCTTTCTTTCTTTCTCTCTCTCTCTCTCTTTCTTTCTTTTTCTTTCTCTTTTTCTTTCTTTCAAG CAGTCCTCCCGCCTCAGTCCCCCAAAATAGTGGGATTACAGGTGTGAGCCACCATGCACAGCCTTACAT AAAGCCTTTTCTAATGAGATGGATAGTAATTAACAAATGTGAGTTTTTGATATTATATAAAGATTTTT ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_000553.6
Synonyms	RECQ3; RECQL2; RECQL3
Summary	This gene encodes a member of the RecQ subfamily of DNA helicase proteins. The encoded nuclear protein is important in the maintenance of genome stability and plays a role in DNA repair, replication, transcription and telomere maintenance. This protein contains a N-terminal 3' to 5' exonuclease domain, an ATP-dependent helicase domain and RQC (RecQ helicase conserved region) domain in its central region, and a C-terminal HRDC (helicase RNase D C-terminal) domain and nuclear localization signal. Defects in this gene are the cause of Werner syndrome, an autosomal recessive disorder characterized by accelerated aging and an elevated risk for certain cancers. [provided by RefSeq, Aug 2017]
Locus ID	7486
MW	78.1

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