MRG15 (MORF4L1) (NM_206839) Human 3' UTR Clone

Specifications

Product Data
Product Name	MRG15 (MORF4L1) (NM_206839) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	Eaf3; FWP006; HsT17725; MEAF3; MORFRG15; MRG15; S863-6
ACCN	NM_206839
Insert Size	1102 bp
Sequence Data	Insert Sequence (showhide) >SC208979 3’UTR clone of NM_206839 The sequence shown below is from the reference sequence of NM_206839. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CCTCCTGAGTACCATCGGAAAGCTGTGTGAGAGGCACTCTCACTCACTTATGTTTGGATCTCCGTAAAC ACATTTTTGTTCTTAGTCTATCTCTTGTACAAACGATGTGCTTTGAAGATGTTAGTGTATAACAATTGA TGTTTGTTTTCTGTTTGATTTTAAACAGAGAAAAAATAAAAGGGGGTAATAGCTCCTTTTTTCTTCTTT CTTTTTTTTTTTCATTTCAAAATTGCTGCCAGTGTTTTCAATGATGGACAACAGAGGGATATGCTGTAG AGTGTTTTATTGCCTAGTTGACAAAGCTGCTTTTGAATGCTGGTGGTTCTATTCCTTTGACACTACGCA CTTTTATAATACATGTTAATGCTATATGACAAAATGCTCTGATTCCTAGTGCCAAAGGTTCAATTCAGT GTATATAACTGAACACACTCATCCATTTGTGCTTTTGTTTTTTTTTATGGTGCTTAAAGTAAAGAGCCC ATCCTTTGCAAGTCATCCATGTTGTTACTTAGGCATTTTATCTTGGCTCAAATTGTTGAAGAATGGTGG CTTGTTTCATGGTTTTTGTATTTGTGTCTAATGCACGTTTTAACATGATAGACGCAATGCATTGTGTAG CTAGTTTTCTGGAAAAGTCAATCTTTTAGGAATTGTTTTTCAGATCTTCAATAAATTTTTTCTTTAAAT TTCAAAGAACAATGTGCTTGTGTTGATGCCTTACAAAAACCATTGTATATTTGTGTATTCCTTCTTGTA TTTAGACAGTGGTTTTTCAGGTGCGTGCTTTGTTTTCTGGTATGGCCTTTATGGAATGAGACGCTTTAG CTTTGGTACGTAGCGCTAATCCATAGCAGCTTTGGCAGTTTGCTGTCTTGAGTCTTAGCTAAAAAGTTA GAAGTTTACATGACTGTTTTTTTTATTTTCCCTAAATTATTACTTACTCTGAGCATTAATTAAGGGCAT TTTCACCTGTGTAAAATTATGGTCAGCTTTTTTCTGTCTATAATTGTTTACTTTTGTGGGTTTACTCTA GAAACATGAGCCAAAAATGTCAATAGACAACACAGTATTAAAATAACCCAAAAGTTGTAAAGGGCAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_206839.3
Synonyms	Eaf3; FWP006; HsT17725; MEAF3; MORFRG15; MRG15; S863-6
Summary	Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Also component of the mSin3A complex which acts to repress transcription by deacetylation of nucleosomal histones. Required for homologous recombination repair (HRR) and resistance to mitomycin C (MMC). Involved in the localization of PALB2, BRCA2 and RAD51, but not BRCA1, to DNA-damage foci.[UniProtKB/Swiss-Prot Function]
Locus ID	10933
MW	43.4

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