S1P (MBTPS1) (NM_003791) Human 3' UTR Clone

Specifications

Product Data
Product Name	S1P (MBTPS1) (NM_003791) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	PCSK8; S1P; SEDKF; SKI-1
ACCN	NM_003791
Insert Size	716 bp
Sequence Data	Insert Sequence (showhide) >SC208990 3’UTR clone of NM_003791 The sequence shown below is from the reference sequence of NM_003791. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GTTCACCCGCCAAAGACCCCTTCGGTGTGACCGGCAGCCTGGCTGACCGTGAGGGCCAGAGAGAGCCTT CACGGACGGCGCTGGTGGGTGAGCCGAGCTGTGGTGGCGGCTGGTTTAAAAGGGATCCAGTTTCCAGCT GCAGGTTTGTTAGAGTCTGTTCTACATGGGCCTGCCCTCCTGTGATGGGCAGAGGCTCCTGGTACATCG AGAAGATTCCTGTGGATCCCGTCAGGAGGGACTTAGTGGCTCTGCCGCCAGTGAGACTTCCCGCCGGCA GCTGTGCGCACCAAAGACTCGGGAGAACTGGAAAGGCTGTCTGGGGTCTTCTGACTGCAGGGGAAGGAT GTACTTTCCAAACAAATGATACAACCCTGACCAAGCTAAAAGACGCTTGTTAAAGGCTATTTTCTATAT TTATTGTTGGGAAAAGTCACTTTAAAGACTTGTGCTATTTGGAAGCAAAGCTATTTTTTTTGTCAGTGG AATGCAGTTTTTTTACTATTCCATCATGAGGAACAACATAGATTCCATGATCTTTTTAATGACAGTACA GACTGAGATTTGAAGGAAACATGCACAAATCTGTAAAACATAGACCTTCGCTTTATTTTTGTAAGTATC ACCTGCCACCATGTTTTGTAATTTGAGGTCTTGATTTCACCATTGTCGGTGAAGAAAATTTTCAATAAA TATGTATTACCCGTCTGAAGCTTAAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_003791.4
Synonyms	PCSK8; S1P; SEDKF; SKI-1
Summary	This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to the cis/medial-Golgi where a second autocatalytic event takes place and the catalytic activity is acquired. It encodes a type 1 membrane bound protease which is ubiquitously expressed and regulates cholesterol or lipid homeostasis via cleavage of substrates at non-basic residues. Mutations in this gene may be associated with lysosomal dysfunction. [provided by RefSeq, Feb 2014]
Locus ID	8720
MW	27.1

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