TRAF6 (NM_145803) Human 3' UTR Clone

Specifications

Product Data
Product Name	TRAF6 (NM_145803) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	MGC:3310; RNF85
ACCN	NM_145803
Insert Size	2000 bp
Sequence Data	Insert Sequence (showhide) >SC209042 3’UTR clone of NM_145803 The sequence shown below is from the reference sequence of NM_145803. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CAGCCACGAAGTACTGATGCAGGGGTATAGCTTGCCCTCACTTGCTCAAAAACAACTACCTGGAGAAAA CAGTGCCTTTCCTTGCCCTGTTCTCAATAACATGCAAACAAACAAGCCACGGGAAATATGTAATATCTA CTAGTGAGTGTTGTTAGAGAGGTCACTTACTATTTCTTCCTGTTACAAATGATCTGAGGCAGTTTTTTC CTGGGAATCCACACGTTCCATGCTTTTTCAGAAATGTTAGGCCTGAAGTGCCTGTGGCATGTTGCAGCA GCTATTTTGCCAGTTAGTATACCTCTTTGTTGTACTTTCTTGGGCTTTTGCTCTGGTGTATTTTATTGT CAGAAAGTCCAGACTCAAGAGTACTAAACTTTTAATAATAATGGATTTTCCTTAAAACTTCAGTCTTTT TGTAGTATTATATGTAATATATTAAAAGTGAAAATCACTACCGCCTTGTGCTAGTGCCCTCGAGAAGAG TTATTGCTCTAGAAAGTTGAGTTCTCATTTTTTTAACCTGTTATAGATTTCAGAGGATTTGAACCATAA TCCTTGGAAAACTTAAGTTCTCATTCACCCCAGTTTTTCCTCCAGGTTGTTACTAAGGATATTCAGGGA TGAGTTTAAACCCTAAATATAACCTTAATTATTTAGTGTAAACATGTCTGTTGAATAATACTTGTTTAA GTGTTCCTTCTGCCTTGCTTACTTATTTCCTTGAGGTTACGAAGTAGCATCTTCCCCAGAGTTTATAAT GCTGAGAACCACGTGGATACCAACTGCTCATTGTTATGCTATGTAACCCTTTTTGTCTATTCAGTGCAG AGTGAATTTCACAGCTCTGCATATGTCTTCATTTGTTTAATGCTTACAAGACAGGAGATGCACACATAC AATCAGCAACATAAAAATTAAAAGTGACCCAAGTAGTCAGCGCATGTGGCATCTCATTGGTGGTGACAG AAGCTATGTGAGCCAGAAGTTTTCAGCTCTTTTGAATACCCTCTGGTTTATTTCGATTAAAAAGAACAA AATTGATTTCCTAAAATCAGAATTTTTTAAAACTTGGGAGATGATTGGAGATACCTAGGAGGTCACCAA ACTAGGATTAGAAGTCACAGTGGTTGTATCACAACTTAGCTTGAGTATGTTGCTGTAGCCTAACAACTG CAGGTTCTGAGAAGGATCCTGTAGAATCCTGGAAGTAACCAGATTTTCCTAATAGGGAGATGATTTTTT TGTGTGCCATCATGTATTTGTTAAAGGCCTATATATAGATATAAAATATCGTGGAATCTAGTTCTCAGG GAGACCCGCAACTAGTATAAGCTTATAAAGGATCTAAAGATCCATCCACCATTTAAAGTTGTCTGGTAA TGAGAGATGACATTGTATCCCCCAGAGAGGCCAAATCAGAGTCGCCAGCCAGCGTTCTAGATCAGCCTT AATTTCAAGAGAAAGCCAAGGACCTCATCTGCAGGGGAGTGTGGTTTTCAGCCCCAGCGAGTGTCACTT TGAACTTTCCCTTTGCTTTTTTCTCTCTTCTCCCTCCCCACCCACCCTTAGGCTCCTGATCTGGTGAGT TTGTTATGGAGTGAAAATAAAAGTCAAGCAGAGACCTTGTTTCCCGTGCCACCATTAGTACCACAAGCT CATGGCTAGTTACCACATTACTTCCTGGCAGTTTGTGTCCCTCAGCTGTGCCTTCCAACCAGCGCCTGA GAATCACTGCATACCACCCTCTAGGTAGGGAAACCTACACTGCTGCTGTTCCTGTGATTATTTTACAAT GAATAAATAATTGTCAAGTTCCATTTAAAAACTGAACAGTAGTATTTTTGTATTTGCGTAGAAAAAGCC TGAAGGAAATATACTAAACTTTTTGTTGGCTTATTTTCCTTTGCGCTTGCTTATATTTTTTACATTTTC TACAATAAATGTGTACTTTTATCGGAGAAAAAAATTAAATGTTGCCACAAAACATTTAATCTCCACGC ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_145803.3
Synonyms	MGC:3310; RNF85
Summary	The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins are associated with, and mediate signal transduction from, members of the TNF receptor superfamily. This protein mediates signaling from members of the TNF receptor superfamily as well as the Toll/IL-1 family. Signals from receptors such as CD40, TNFSF11/RANCE and IL-1 have been shown to be mediated by this protein. This protein also interacts with various protein kinases including IRAK1/IRAK, SRC and PKCzeta, which provides a link between distinct signaling pathways. This protein functions as a signal transducer in the NF-kappaB pathway that activates IkappaB kinase (IKK) in response to proinflammatory cytokines. The interaction of this protein with UBE2N/UBC13, and UBE2V1/UEV1A, which are ubiquitin conjugating enzymes catalyzing the formation of polyubiquitin chains, has been found to be required for IKK activation by this protein. This protein also interacts with the transforming growth factor (TGF) beta receptor complex and is required for Smad-independent activation of the JNK and p38 kinases. This protein has an amino terminal RING domain which is followed by four zinc-finger motifs, a central coiled-coil region and a highly conserved carboxyl terminal domain, known as the TRAF-C domain. Two alternatively spliced transcript variants, encoding an identical protein, have been reported. [provided by RefSeq, Feb 2012]
Locus ID	7189
MW	76.9

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