CBLB (NM_170662) Human 3' UTR Clone

Specifications

Product Data
Product Name	CBLB (NM_170662) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	Cbl-b; Nbla00127; RNF56
ACCN	NM_170662
Insert Size	730 bp
Sequence Data	Insert Sequence (showhide) >SC209114 3' UTR clone of NM_170662 The sequence shown below is from the reference sequence of NM_170662. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon CAATTGGCAGAGCTCAGAATTCAAGCGATCGC TTTGCCTTCCCTCCTCCAGTATCCCCACGTCTAAATCTATAGCAGCCAGAACTGTAGACACCAAAATGGA AAGCAATCGATGTATTCCAAGAGTGTGGAAATAAAGAGAACTGAGATGGAATTCAAGAGAGAAGTGTCTC CTCCTCGTGTAGCAGCTTGAGAAGAGGCTTGGGAGTGCAGCTTCTCAAAGGAGACCGATGCTTGCTCAGG ATGTCGACAGCTGTGGCTTCCTTGTTTTTGCTAGCCATATTTTTAAATCAGGGTTGAACTGACAAAAATA ATTTAAAGACGTTTACTTCCCTTGAACTTTGAACCTGTGAAATGCTTTACCTTGTTTACAGTTTGGCAAA GTTGCAGTTTGTTCTTGTTTTTAGTTTAGTTTTGTTTTGGTGTTTTGATACCTGTACTGTGTTCTTCACA GACCCTTTGTAGCGTGGTCAGGTCTGCTGTAACATTTCCCACCAACTCTCTTGCTGTCCACATCAACAGC TAAATCATTTATTCATATGGATCTCTACCATCCCCATGCCTTGCCCAGGTCCAGTTCCATTTCTCTCATT CACAAGATGCTTTGAAGGTTCTGATTTTCAACTGATCAAACTAATGCAAAAAAAAAAAAGTATGTATTCT TCACTACTGAGTTTCTTCTTTGGAAACCATCACTATTGAGAGATGGGAAAAACCTGAATGTATAAAGCAT TTATTTGTCAATAAACTGCCTTTTGTAAGG ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_170662.3
Synonyms	Cbl-b; Nbla00127; RNF56
Summary	This gene encodes an E3 ubiquitin-protein ligase which promotes proteosome-mediated protein degradation by transferring ubiquitin from an E2 ubiquitin-conjugating enzyme to a substrate. The encoded protein is involved in the regulation of immune response by limiting T-cell receptor, B-cell receptor, and high affinity immunoglobulin epsilon receptor activation. Studies in mouse suggest that this gene is involved in antifungal host defense and that its inhibition leads to increased fungal killing. Manipulation of this gene may be beneficial in implementing immunotherapies for a variety of conditions, including cancer, autoimmune diseases, allergies, and infections. [provided by RefSeq, Sep 2017]
Locus ID	868

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