NUP98 (NM_139131) Human 3' UTR Clone
CAT#: SC209294
3' UTR clone of nucleoporin 98kDa (NUP98) transcript variant 2 for miRNA target validation
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CNY 4,845.00
货期*
3周
规格
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经常一起买 (2)
Specifications
Product Data | |
Product Name | NUP98 (NM_139131) Human 3' UTR Clone |
Vector | pMirTarget |
Synonyms | ADIR2; NUP96; Nup98-96; NUP196 |
ACCN | NM_139131 |
Insert Size | 1020 bp |
Sequence Data |
>SC209294 3’UTR clone of NM_139131
The sequence shown below is from the reference sequence of NM_139131. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CCACCTCAGGTAGAGAAAAAAGGACAGTGAATTTGAATGGAATCCGTGATACCGAAGTTGAAAGCAAGT CATTCAGCTAATACAAAGCTGTTTTATGACCCTTGGAACTTTGAAGAGTACAAACATTGGCAATCACGT TGAAACAAGTGCAAGGGAGGGCGTGAGGTCTTGCAGGCATCTGTCTTTTTACTGGAGAGATTTAAAGAA TTCTCTTGCTGTTTGGATTATTCCTCTACAGATTGTCATTTTTAAACCCTTTGTTCTCTCTCATTTGGA CTTGCTGAATTCTCTGCTCAGTGATTAACTTAAGATTTGCTCATGTGGGTTCATGCACAGTAAATTCTG CCTTTATTGACTACCTGATGTGCAGTTTAATCTTTTTCTTTACCTCCATGGTTTTTTAAAAGTTAAATT AGCTTTCTGAAAGGGTTTTTAATCTCCATTTTTTTAAAGTTGTTTGCTTATACTTCGGGTAACCTTGAT ATTTGTATTTTAATAGTACATAATCTTTATGAAAAATAGTTTGGGAATGTAAATGAATTATTATTTGGC TTGGGGAGATTAGGGCCTACATTGTTTATCGCAATTACTTGTATCATTGATACGGGATTTCTTTGTAAA GCATCCTCTACCTCTCAGCTGCTGAAAGCTAGACCTTTGGTATTTTCCATGCTATAATTCTTATGGCTG CTGAAATGTGTGGTTTTTATGATTTATTAAATAATCTCTTAGGAGGCATTTCTGGAGAATGTGTGTATA TACATGTTTGCGCGTACAGGGGAGGGGAGGGTATGATAAATGTGGGAAACTGGAAATATATTGACTTTT ATGTTTATAATCTTGGTAGCATTTAGAATGCCCCTAAGAAATCTCCATTGACAAATGAAATGCTATAGA CTTGGTTTTCCAGTTATCCATATTCATTTTGTCTGTCATATGCTTTGTATCATCTCCTTCTTTCCTAAT TTTTTATAACCTTATATATATATTTATTATAAATATATGTATTTCTGAGGGAAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG |
Restriction Sites | SgfI-MluI |
OTI Disclaimer | Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs). |
Reference Data | |
RefSeq | NM_139131.5 |
Synonyms | ADIR2; NUP96; Nup98-96; NUP196 |
Summary | Nuclear pore complexes (NPCs) regulate the transport of macromolecules between the nucleus and cytoplasm, and are composed of many polypeptide subunits, many of which belong to the nucleoporin family. This gene belongs to the nucleoporin gene family and encodes a 186 kDa precursor protein that undergoes autoproteolytic cleavage to generate a 98 kDa nucleoporin and 96 kDa nucleoporin. The 98 kDa nucleoporin contains a Gly-Leu-Phe-Gly (GLGF) repeat domain and participates in many cellular processes, including nuclear import, nuclear export, mitotic progression, and regulation of gene expression. The 96 kDa nucleoporin is a scaffold component of the NPC. Proteolytic cleavage is important for targeting of the proteins to the NPC. Translocations between this gene and many other partner genes have been observed in different leukemias. Rearrangements typically result in chimeras with the N-terminal GLGF domain of this gene to the C-terminus of the partner gene. Alternative splicing results in multiple transcript variants encoding different isoforms, at least two of which are proteolytically processed. Some variants lack the region that encodes the 96 kDa nucleoporin. [provided by RefSeq, Feb 2016] |
Locus ID | 4928 |
MW | 39.5 |
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