KCNA5 (NM_002234) Human 3' UTR Clone
CAT#: SC209953
3' UTR clone of potassium voltage-gated channel shaker-related subfamily member 5 (KCNA5) for miRNA target validation
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CNY 4,845.00
货期*
3周
规格
Cited in 1 publication. |
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经常一起买 (2)
Specifications
Product Data | |
Product Name | KCNA5 (NM_002234) Human 3' UTR Clone |
Vector | pMirTarget |
Synonyms | ATFB7; HCK1; HK2; HPCN1; KV1.5; PCN1 |
ACCN | NM_002234 |
Insert Size | 829 bp |
Sequence Data |
>SC209953 3’UTR clone of NM_002234
The sequence shown below is from the reference sequence of NM_002234. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CTGGACACCAGCCGGGAAACAGATTTGTGAAAGGAGATTCAGGCAGACTGGTGGCAGTGGAGTAGGGAA TGGGAGGCTTGCTGAACATGGATATCTACATTATACCGCAGAGTATTTGAAGTCACACTGTAACCTCAG TCTACCCCTCTCCTTTCACTCCTTTCCTCCCTCCCTCGATCCCCCCATTTTCTCTATTCTTTCCATGAC ACCCAAGGGTCGCCTATTTTTAAAAAGTACCACATTCCATGACGCAGGAGCTGTGGAAATGGTGAGCGC TGTGAGATGGATGTATTTGTAGCCAGTCTCCTATACCCAGCAGAGGGATAACCCAAACAAAAATGACTC TAAATAGCCCAGATCCCAAGAGATTATGTAACTCCTCCATCCATGTGTTCCAAATTTGCTTTACATATG ATTGTATTTGTGTATAGGGGAAAATATTATTTTTATGCCTGGTAAGTGGCTTTTTGTACTGTAGTTCAG ATAGAGATATTTTGGGTATATTTTCAAGATACATGTTGTATTTATGGAAGAAAGAGTTGTCCTGATGTT TTTCTGTGTTACTTATATTAGAGTCAGAGATCTTGGTATGGGCTGTTCTGTTTCCTGTGTCTCCAAGCC TCTGTCTTTTCTGGGATGTGGTATTGGTGCTTTGTGTCTAGGGCAGAGTATGTTCTTGAAGAAAGGCAA ATCTGACTTTTTCTGTGCGCCTTAAACAATTCTTGTAACTTTCTTCAAAAAGCATTTTAATGATATTGG AGGAATACTTCTGATAATTTATTGTCTTTATTTTTATCCCAGGAAATAAAAGGTTACCTTGTTGAGGCAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG |
Restriction Sites | SgfI-MluI |
OTI Disclaimer | Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs). |
Reference Data | |
RefSeq | NM_002234.4 |
Synonyms | ATFB7; HCK1; HK2; HPCN1; KV1.5; PCN1 |
Summary | Potassium channels represent the most complex class of voltage-gated ino channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, the function of which could restore the resting membrane potential of beta cells after depolarization and thereby contribute to the regulation of insulin secretion. This gene is intronless, and the gene is clustered with genes KCNA1 and KCNA6 on chromosome 12. Defects in this gene are a cause of familial atrial fibrillation type 7 (ATFB7). [provided by RefSeq, May 2012] |
Locus ID | 3741 |
MW | 32.7 |
Citations (1)
The use of this cDNA Clones has been cited in the following citations: |
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miR-1 is increased in pulmonary hypertension and downregulates Kv1.5 channels in rat pulmonary arteries
,Mondejar-Parreño, G;Callejo, M;Barreira, B;Morales-Cano, D;Esquivel-Ruiz, S;Moreno, L;Cogolludo, A;Perez-Vizcaino, F;,
J. Physiol. (Lond.) 2018
,PubMed ID 29717493
[KCNA5]
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