E2F4 (NM_001950) Human 3' UTR Clone
CAT#: SC209960
3' UTR clone of E2F transcription factor 4 p107/p130-binding (E2F4) for miRNA target validation
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CNY 4,845.00
货期*
3周
规格
Cited in 2 publications. |
Product images
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经常一起买 (2)
Specifications
Product Data | |
Product Name | E2F4 (NM_001950) Human 3' UTR Clone |
Vector | pMirTarget |
Synonyms | E2F-4 |
ACCN | NM_001950 |
Insert Size | 825 bp |
Sequence Data |
>SC209960 3’UTR clone of NM_001950
The sequence shown below is from the reference sequence of NM_001950. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CTCTTTGATGTGCCTGTTCTCAACCTCTGACTGACAGGGACATGCCCTGTGTGGCTGGGACCCAGACTG TCTGACCTGGGGGTTGCCTGGGGACCTCTCCCACCCGACCCCTACAGAGCTTGAGAGCCACAGACGCCT GGCTTCTCCGGCCTCCCCTCACCGCACAGTTCTGGCCACAGCTCCCGCTCCTGTGCTGGCACTTCTGTG CTCGCAGAGCAGGGGAACAGGACTCAGCCCCCATCACCGTGGAGCCAAAGTGTTTGCTTCTCCCTTTCT GCGGCCTTCGCCAGCCCAGGCTCGGCTGCCACCCAGTGGCACAGAACCGAGGAGCTGCCATTACCCCCC ATAGGGGGCAGTGTCTTGTTCCTGCCAGCCTCAGTGTCTTGCTTCTGCCAGCTCCTTCCCCTAGGAGGG AAGGGTGGGGTGGAACTGGGCACATGCCAGCACCACTTCTAGCTTCCTTCGCTATCCCCCACCCCCTGA CCCTCCAGCTCCTCCTGGCCCTCTCACGTGCCCACTTCTGCTGGGCCTTTAGCCCTAGAACCTGCAGGT GGTGGGGGCGGCTACCAAGAAGGAACAGAGGTCTCTGGGGAGGAGTCTGGGTGGTCCAGCCCTGATGAT TGGCCCCACCTCCTGCTGCCCCATAACCCTCTCTTCATTTCGGCTTTTTCATTTACCCTCATTTAGAGC CATTTGCAGAGATTTAGAAAGATTTACAGTAACGAATGGATTCCTATATAAAGATTATTTTTATACTTT TTGCAGCAAAAGGAAATTGTAATATTTGTACAGTGTTCAAGTGAATAAAAACCATGCCTAAGGCTA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG |
Restriction Sites | SgfI-MluI |
OTI Disclaimer | Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs). |
Reference Data | |
RefSeq | NM_001950.4 |
Synonyms | E2F-4 |
Summary | The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein binds to all three of the tumor suppressor proteins pRB, p107 and p130, but with higher affinity to the last two. It plays an important role in the suppression of proliferation-associated genes, and its gene mutation and increased expression may be associated with human cancer. [provided by RefSeq, Jul 2008] |
Locus ID | 1874 |
MW | 29.5 |
Citations (2)
The use of this cDNA Clones has been cited in the following citations: |
---|
Establishment of the TBX-code reveals aberrantly activated T-box gene TBX3 in Hodgkin lymphoma
,null,
PLoS ONE
,PubMed ID 34807923
[E2F4]
|
Inhibition of CK1ε potentiates the therapeutic efficacy of CDK4/6 inhibitor in breast cancer
,null,
Nature Communications
,PubMed ID 34508104
[E2F4]
|
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