E2F4 (NM_001950) Human 3' UTR Clone

Specifications

Product Data
Product Name	E2F4 (NM_001950) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	E2F-4
ACCN	NM_001950
Insert Size	825 bp
Sequence Data	Insert Sequence (showhide) >SC209960 3’UTR clone of NM_001950 The sequence shown below is from the reference sequence of NM_001950. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CTCTTTGATGTGCCTGTTCTCAACCTCTGACTGACAGGGACATGCCCTGTGTGGCTGGGACCCAGACTG TCTGACCTGGGGGTTGCCTGGGGACCTCTCCCACCCGACCCCTACAGAGCTTGAGAGCCACAGACGCCT GGCTTCTCCGGCCTCCCCTCACCGCACAGTTCTGGCCACAGCTCCCGCTCCTGTGCTGGCACTTCTGTG CTCGCAGAGCAGGGGAACAGGACTCAGCCCCCATCACCGTGGAGCCAAAGTGTTTGCTTCTCCCTTTCT GCGGCCTTCGCCAGCCCAGGCTCGGCTGCCACCCAGTGGCACAGAACCGAGGAGCTGCCATTACCCCCC ATAGGGGGCAGTGTCTTGTTCCTGCCAGCCTCAGTGTCTTGCTTCTGCCAGCTCCTTCCCCTAGGAGGG AAGGGTGGGGTGGAACTGGGCACATGCCAGCACCACTTCTAGCTTCCTTCGCTATCCCCCACCCCCTGA CCCTCCAGCTCCTCCTGGCCCTCTCACGTGCCCACTTCTGCTGGGCCTTTAGCCCTAGAACCTGCAGGT GGTGGGGGCGGCTACCAAGAAGGAACAGAGGTCTCTGGGGAGGAGTCTGGGTGGTCCAGCCCTGATGAT TGGCCCCACCTCCTGCTGCCCCATAACCCTCTCTTCATTTCGGCTTTTTCATTTACCCTCATTTAGAGC CATTTGCAGAGATTTAGAAAGATTTACAGTAACGAATGGATTCCTATATAAAGATTATTTTTATACTTT TTGCAGCAAAAGGAAATTGTAATATTTGTACAGTGTTCAAGTGAATAAAAACCATGCCTAAGGCTA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_001950.4
Synonyms	E2F-4
Summary	The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein binds to all three of the tumor suppressor proteins pRB, p107 and p130, but with higher affinity to the last two. It plays an important role in the suppression of proliferation-associated genes, and its gene mutation and increased expression may be associated with human cancer. [provided by RefSeq, Jul 2008]
Locus ID	1874
MW	29.5

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