MTREX (NM_015360) Human 3' UTR Clone

Specifications

Product Data
Product Name	MTREX (NM_015360) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	Dob1; fSAP118; KIAA0052; Mtr4; SKIV2L2
ACCN	NM_015360
Insert Size	813 bp
Sequence Data	Insert Sequence (showhide) >SC210234 3' UTR clone of NM_015360 The sequence shown below is from the reference sequence of NM_015360. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon CAATTGGCAGAGCTCAGAATTCAAGCGATCGC TTTGCTGCCAGCCTCTACTTGTAGAGTCAGCTAAAGGAATGTGAGATTTTAAATTATTGACCACCTGTTT GATTACAGTTGACTACAAATGCCTGCAAGTGTGGATTTGGTTCTCCCATACATTTTAATATGTATTATAT TTAAATCAAACATCATTCATAGAAAGCATATTACATACATGTTTATACATAAGCATTACATTTTTTTAAT AAAAATGTATACAGGTGGGGCACTGTTTTGGTGGAAGGCTTGGAGTTTTTTTAATGAGTTTAGAGCTATT AGATAACCACTGAGTTAAAGGTAACTATGTACACACAAAGTGTGCATCCAAGAGGCATAGCAGCAGCAGA AGTCTTTAAAGGCTTGTACACCAGGAAGAAAGATGCATCCTCTTGCCTTGTGGCAATCATTTTCCTTTAG AAAACAGGCCAGCTTCACCTGGGCACCCTGCTGCCTTTCAAGGCTGGTGATTGCTCGGATAGTGATTCCC AGTTGTTGGTGTTTCATGCAGAGTTGTATGAGAGTCCTCCTCTTTTCTTTCTTTAAAAGAAGTTCTTTCT TTGAAGAAATCCGATACATATACAGCCTACAGTGCAAAATATTTAATGGTATAATTTAGATCAAGTTAAA AACTACATACAAAGTTGTGATCAACAGCATCCTAAGATAAATATAAACAAAAGGATATACTTTGAGGTGT ACAGATTAAGCATATAAAAAATTAGAGACTAACTGGGATTTTTTAAAGATTATTCCAAATTAAGAGTTGC TTTGTTATGCCTTCAGCAAATAGCTTCATTTTGCCAATACTGA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_015360.4
Synonyms	Dob1; fSAP118; KIAA0052; Mtr4; SKIV2L2
Summary	Component of exosome targeting complexes. Subunit of the trimeric nuclear exosome targeting (NEXT) complex, a complex that directs a subset of non-coding short-lived RNAs for exosomal degradation. Subunit of the trimeric poly(A) tail exosome targeting (PAXT) complex, a complex that directs a subset of long and polyadenylated poly(A) RNAs for exosomal degradation. The RNA exosome is fundamental for the degradation of RNA in eukaryotic nuclei. Substrate targeting is facilitated by its cofactor MTREX, which links to RNA-binding protein adapters (PubMed:27871484). Associated with the RNA exosome complex and involved in the 3'-processing of the 7S pre-RNA to the mature 5.8S rRNA (PubMed:17412707, PubMed:29107693). May be involved in pre-mRNA splicing.[UniProtKB/Swiss-Prot Function]
Locus ID	23517

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