CHIT1 (NM_003465) Human 3' UTR Clone

Specifications

Product Data
Product Name	CHIT1 (NM_003465) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	CHI3; CHIT; CHITD
ACCN	NM_003465
Insert Size	840 bp
Sequence Data	Insert Sequence (showhide) >SC210235 3’UTR clone of NM_003465 The sequence shown below is from the reference sequence of NM_003465. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC AACTCCTGCAAATGCTGCACCTGGAATTGAGTCGCTAAAGCCCCTCCAGTCCCAGCTTTGAGGCTGGGC CCAGGATCACTCTACAGCCTGCCTCCTGGGTTTTCCCTGGGGGCCGCAATCTGGCTCCTGCAGGCCTTT CTGTGGTCTTCCTTTATCCAGGCTTTCTGCTCTCAGCCTTGCCTTCCTTTTTTCTGGGTCTCCTGGGCT GCCCCTTTCACTTGCAAAATAAATCTTTGGTTTGTGCCCCTCTTCCCAAAGATGTGGTGACTTAAGAGG CTCTCTAAGCACACTGTTGACTCCAAAACATCCGCAGGTCAGAGCCAGGTGGGAAGGTGGTCCGTGCAG GATGTGCCAGGCCCTGTGGCAGGTCTTGCCCCATGAGTCCATATGCCAGTGGGCAGTTTCCAGTACACA GGTGATGGCAGCCAGAGCGCGGCCCCAAGTGCAACACGTTCTTTGGTTATTGGCTCAGAAGCCTGGAAA CAGGAGCTTCTGCGGACCTTCACGCACGTGTTATTCCCAAAATGCCACTAGATGGCAGCAGAGAAGAAC TTTTCCCTGATTTAAGCGCTCTGCGAGCAGCCACTCAGCATTACACTAAGAATTCAGACCCCTGGTACT CAGGGGTCTTCGAGATAAATCCTGTTTGGGCCCTTTGCAGGCCCTATCTCACCTACTGCCCCCGTTCAC CAGATGAAGAAGGAACAATGATTATTCTCACTTTATAGGCATTTAAACTGAAGACTGATTCTAACCAAT TCTGAGTCCAGAACCAAGGCCTGAAATGGGCCAGAGAGCATGCACACGGTGTCCTGGTTAAATAAAGTC ATCCCAACATTC ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_003465.3
Synonyms	CHI3; CHIT; CHITD
Summary	Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens. Several alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jan 2012]
Locus ID	1118
MW	30.9

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