LEFTY2 (NM_003240) Human 3' UTR Clone

Specifications

Product Data
Product Name	LEFTY2 (NM_003240) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	EBAF; LEFTA; LEFTYA; TGFB4
ACCN	NM_003240
Insert Size	868 bp
Sequence Data	Insert Sequence (showhide) >SC210384 3’UTR clone of NM_003240 The sequence shown below is from the reference sequence of NM_003240. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GCGCTCGTGCCAAGGAGGCTCCAGCCATAGGCGCCTGGTGTATCCATTGAGCCCTCTAACTGAACGTGT GCATAGAGGTGGTCTTAATGTAGGTCTTAACTTTATACTTAGCAAGTTACTCCATCCCAATTTAGTGCT CCTGTGTGACCTTCGCCCTGTGTCCTTCCATTTCCTGTCTTTCCCGTCCATCACCCATCCTAAGCACTT ACGTGAGTAAATAATGCAGCTCAGATGCTGAGCTCTAGTAGGAAATGCTGGCATGCTGATTACAAGATA CAGCTGAGCAATGCACACATTTTCAGCTGGGAGTTTCTGTTCTCTGGCAAATTCTTCACTGAGTCTGGA ACAATAATACCCTATGATTAGAACTGGGGAAACAGAACTGAATTGCTGTGTTATATGAGGAATTAAAAC CTTCAAATCTCTATTTCCCCCAAATACTGACCCATTCTGGACTTTTGTAAACATACCTAGGCCCCTGTT CCCCTGAGAGGGTGCTAAGAGGAAGGATGAAGGGCTTCAGGCTGGGGGCAGTGGACAGGGAATTGGGAT ACCTGGATTCTGGTTCTGACAGGGCCACAAGCTAGGATCTCTAACAAACGCAGAAGGCTTTGGCTCGTC ATTTCCTCTTAAAAAGGAGGAGCTGGGCTTCAGCTCTAAGAACTTCATTGCCCTGGGGATCAGACAGCC CCTACCTACCCCTGCCCACTCCTCTGGAGACTGAGCCTTGCCCGTGCATATTTAGGTCATTTCCCACAC TGTCTTAGAGAACTTGTCACCAGAAACCACATGTATTTGCATGTTTTTTGTTAATTTAGCTAAAGCAAT TGAATGTAGATACTCAGAAGAAATAAAAAATGATGTTTCA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_003240.5
Synonyms	EBAF; LEFTA; LEFTYA; TGFB4
Summary	This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein, which plays a role in left-right asymmetry determination of organ systems during development. The protein may also play a role in endometrial bleeding. Mutations in this gene have been associated with left-right axis malformations, particularly in the heart and lungs. Some types of infertility have been associated with dysregulated expression of this gene in the endometrium. This gene is closely linked to both a related family member and a related pseudogene. This gene encodes multiple isoforms that may undergo similar proteolytic processing. [provided by RefSeq, Aug 2016]
Locus ID	7044
MW	33

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