GSTM5 (NM_000851) Human 3' UTR Clone

Specifications

Product Data
Product Name	GSTM5 (NM_000851) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	GSTM5-5; GTM5
ACCN	NM_000851
Insert Size	872 bp
Sequence Data	Insert Sequence (showhide) >SC210499 3’UTR clone of NM_000851 The sequence shown below is from the reference sequence of NM_000851. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GGAAAGTCAGCTACATGGAACAGCAAATAGGGCCCAGTGATGCCAGAAGATGGGAGGGAGGAGCCAACC TTGCTGCCTGCGACCCTGGAGGACAGCCTGACTCCCTGGACCTGCCTTCTTCCTTTTTCCTTCTTTCTA CTCTCTTCTCTTCCCCAAGGCCTCATTGGCTTCCTTTCTTCTAACATCATCCCTCCCCGCATCGAGGCT CTTTAAAGCTTCAGCTCCCCACTGTCCTCCATCAAAGTCCCCCTCCTAACGTCTTCCTTTCCCTGCACT AACGCCAACCTGACTGCTTTTCCTGTCAGTGCTTTTCTCTTCTTTGAGAAGCCAGACTGATCTCTGAGC TCCCTAGCACTGTCCTCAAAGACCATCTGTATGCCCTGCTCCCTTTGCTGGGTCCCTACCCCAGCTCCG TGTGATGCCCAGTAAAGCCTGAACCATGCCTGCCATGTCTTGTCTTATTCCCTGAGGCTCCCTTGACTC AGGACTGTGCTCGAATTGTGGGTGGTTTTTTGTCTTCTGTTGTCCACAGCCAGAGCTTAGTGGATGGGT GTGTGTGTGTGTGTGTTGGGGGTGGTGATCAGGCAGGTTCATAAATTTCCTTGGTCATTTCTGCCCTCT AGCCACATCCCTCTGTTCCTCACTGTGGGGATTACTACAGAAAGGTGCTCTGTGCCAAGTTCCTCACTC ATTCGCGCTCCTGTAGGCCGTCTAGAACTGGCATGGTTCAAAGAGGGGCTAGGCTGATGGGGAAGGGGG CTGAGCAGCTCCCAGGCAGACTGCCTTCTTTCACCCTGTCCTGATAGACTTCCCTGATCTAGATATCCT TCGTCATGACACTTCTCAATAAAACGTATCCCACCGTATTGTAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_000851.4
Synonyms	GSTM5-5; GTM5
Summary	Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Diversification of these genes has occurred in regions encoding substrate-binding domains, as well as in tissue expression patterns, to accommodate an increasing number of foreign compounds. [provided by RefSeq, Jul 2008]
Locus ID	2949
MW	31.8

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