LILRB2 (NM_005874) Human 3' UTR Clone

Specifications

Product Data
Product Name	LILRB2 (NM_005874) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	CD85D; ILT-4; ILT4; LIR-2; LIR2; MIR-10; MIR10
ACCN	NM_005874
Insert Size	901 bp
Sequence Data	Insert Sequence (showhide) >SC210718 3’UTR clone of NM_005874 The sequence shown below is from the reference sequence of NM_005874. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC AGCATCTACGCCACCCTGGCCATCCACTAGCCCGGAGGGTACGCAGACTCCACACTCAGTAGAAGGAGA CTCAGGACTGCTGAAGGCACGGGAGCTGCCCCCAGTGGACACCAATGAACCCCAGTCAGCCTGGACCCC TAACAAAGACCATGAGGAGATGCTGGGAACTTTGGGACTCACTTGATTCTGCAGTCGAAATAACTAATA TCCCTACATTTTTTAATTAAAGCAACAGACTTCTCAATAATCAATGAGTTAACCGAGAAAACTAAAATC AGAAGTAAGAATGTGCTTTAAACTGAATCACAATATAAATATTACACATCACACAATGAAATTGAAAAA GTACAAACCACAAATGAAAAAAGTAGAAACGAAAAAAAAAAACTAGGAAATGAATGACGTTGGCTTTCG TATAAGGAATTTAGAAAAAGAATAACCAATTATTCCAAATGAAGGTGTAAGAAAGGGAATAAGAAGAAG AAGAGTTGCTCATGAGGAAAAACCAAAACTTGAAAATTCAACAAAGCCAATGAAGCTCATTCTTGAAAA TATTAATTACAGTCATAAATCCTAACTACATTGAGCAAGAGAAAGAAAGAGCAGGCACGCATTTCCATA TGGGAGTGAGCCAGCAGACAGCCCAGCAGATCCTACACACATTTTCACAAACTAACCCCAGAACAGGCT GCAAACCTATACCAATATACTAGAAAATGCAGATTAAATGGATGAAATATTCAAAACTGGAGTTTACAT AATGAACGTAAGAGTAATCAGAGAATCTGACTCATTTTAAATGTGTGTGTATGTGTGTGTATATATATG TGTGTGTGTGTGTGTGTGTGTGTGTGTGAAAAACATTGACTGTAATAAAAATGTTCCCATCGTATCAAC TCCA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_005874.5
Synonyms	CD85D; ILT-4; ILT4; LIR-2; LIR2; MIR-10; MIR10
Summary	This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Locus ID	10288
MW	34.6

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