CLCN3 (NM_173872) Human 3' UTR Clone

Specifications

Product Data
Product Name	CLCN3 (NM_173872) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	ClC-3; CLC3
ACCN	NM_173872
Insert Size	2000 bp
Sequence Data	Insert Sequence (showhide) >SC211309 3’UTR clone of NM_173872 The sequence shown below is from the reference sequence of NM_173872. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GTTTATTTGTTGAATAGCACAACTCTTTAACCTGAGGGAGTCATCTACTTTTTTTTCCTCCTTTACAAA AAAAGAAAGGAAATATAAAAGCCGGGTTTTTGCAACATGGTTTGCAAATAATGCTGGTGGAATGGAGGA GTTGTTTGGGGAGGGAAAGGAGAGAGAAGGAAAGGAGTGAGGTATTTCCCGTCTAACAGAAAGCAGCGT ATCAACTCCTATTGTTCTGCACTGGATGCATTCAGCTGAGGATGTGCCTGATAGTGCAGGCTTGCGCCT CAACAGAGATGACAGCAGAGTCCTCGAGCACCTGGCCTGTTGCTCCAACATTGCAAAGACACATTATCA GTCCCTATTTCTAGAGGGATTACTTTGAATTGAGCCATCTATAAAACTGCAAGGTCTTGCCCTTTTTTT TAATCAAAACTGTTCTGTTTAATTCATGAATTGTATAGTTAAGCATTACCTTTCTACATTCCAGAAGAG CCTTTATTTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTACTGAGCTGTAACAAAGCCTCTTTAAAT CGGTGTATCCTTTTGAAGCAGTCCTTTCTCATATTGAGATGTACTGTGATTTTACTGAGGTTTCATCAC AAGAAGGGAGTGTTTCTTGTGCCATTAACCATGTAGTTTGTACCATCACTAAATGCTTGGAACAGTACA CATGCACCACAACAAAGGCTCATCAAACAGGTAAAGTCTCGAAGGAAGCGAGAACGAAATCTCTCATTG TGTGCCGTGTGGCTCAAAACCGAAAACAATGAAGCTTGGTTTTAAAGGATAAAGTTTTCTTTTTTGTTT TCCTCTCAGACTTTATGGATAATGTGACCGGGTCTTATGCAAATTTTCTATTTCTAAAACTACTACTAT GATATACAAGTGCTGTTGAGCATAATTAAATAAAATGCTGCTGCTTTGACAGTAAAGAGAAGGAAGTAT TCTGATTAGCTGTATCTGGTATTAATTGCATGTTAAAACACTGGAATTTTTAAAATTGAAATTAGATCA GTCATTCTTTTCTTTTCTCAAGATATCTCATGGCTGACACTGAAGAAGAAATGTAATTCATAACTTGCA CTAAATGTATATTTTTTTTCTTAAAAATTTACCATTCTTATTTATATTTTTATGGATTAAAATTTATAA AATACAGATCAGTTAATATTGCACTTAAGTAATTTTACCTTTTTAATGTGATTTTTATAGAATAATTCA GACTTACAAATACAGAGATATGAACAAAGTTTACAGTGGGAACAAAGGTTTAAAAAAAGGTTGTGGTTC TCTCTCTGTGATCCAGTGTGCACATAAACCTTTCTCTGATCTTTCACTGCCATCCTCTGGATTATGTCT TCTGACCTGTCCATTTTGACCCATTAACTGGAAAGTTGAAAAACTACATTAACTGGAAAGTTGAAAAAC TACATTACTTTGGAGAATAAAACCGAAAGTTCGTGTATACCTTCTTAAAAAAAAAATCAAACCAAAAAT GTGAAAACAATAGAATTGCAAAGATAGCAGTTAAAATTTTAATCTGAAAATAACCTTTGAATCTCGGGC TAGGTTACGTCCATATTTGAAGTGGTCAGTGATGGTTTGAACATTTTTTGCAGGATGAGTGAAAATGCA CTGGATTATATTTGGGATTTTTGTTTTTGGAATTGTCTGTTTTAATCACAGCCTTAATTCACAATTGGC AAAGGCAGTTTACTCAAAGGACTGGGCTAAATATTCTGTAATTATGCATTTTTGATAGGAAAATGAAAT TTTTGCAAACAGACATTTTCTTTTTTTTTGGCTGGAGTGCAGTGGGGCATGGTCTTGGCTCACTGCAGC GTTGACCACCTGGGCTCAAGTGATACTCCCGCCTCAGCCACCCAAGTAGCTGGCACTACGGGCACACGC CACCATGCCCAGCTAATTTTTTTGTATTTTTAGTAGAGATGGGGTTTTGCCATGCTGCCCAGGCTGGT ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_173872.4
Synonyms	ClC-3; CLC3
Summary	This gene encodes a member of the voltage-gated chloride channel (ClC) family. The encoded protein is present in all cell types and localized in plasma membranes and in intracellular vesicles. It is a multi-pass membrane protein which contains a ClC domain and two additional C-terminal CBS (cystathionine beta-synthase) domains. The ClC domain catalyzes the selective flow of Cl- ions across cell membranes, and the CBS domain may have a regulatory function. This protein plays a role in both acidification and transmitter loading of GABAergic synaptic vesicles, and in smooth muscle cell activation and neointima formation. This protein is required for lysophosphatidic acid (LPA)-activated Cl- current activity and fibroblast-to-myofibroblast differentiation. The protein activity is regulated by Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) in glioma cells. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]
Locus ID	1182
MW	77.1

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