G protein coupled receptor 30 (GPER1) (NM_001039966) Human 3' UTR Clone

Specifications

Product Data
Product Name	G protein coupled receptor 30 (GPER1) (NM_001039966) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	CEPR; CMKRL2; DRY12; FEG-1; GPCR-Br; GPER; GPR30; LERGU; LERGU2; LyGPR; mER
ACCN	NM_001039966
Insert Size	984 bp
Sequence Data	Insert Sequence (showhide) >SC211432 3’UTR clone of NM_001039966 The sequence shown below is from the reference sequence of NM_001039966. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC TCGGATGTGAGGTTCAGCAGTGCCGTGTAGACAGCCTTGGCCGCATAGGCCCAGCCAGGGTGTGACTCG GGAGCTGCACACACCTGGGTGGACACAAGGCACGGCCACGTCATGTCTCTAAACTGCGGTCAGATGTGG CTTCTGGCTCCTCGGGGCCTCGCGAGGGTCACGCTTGCCTGGTCACCCTGGGGCTGCTTAGGAAACCTC ACGACTGGTCACCTTGCACTCCTCACACAGAATTGCTACAATCCCAAAGCGCTCGCCCCGCAGGGTCCA AAGGCCAGCGGTGACCAGCCTGTCACCCAGCTCCTCCCCGCCAACCCTGCCTGCCGCTGCACCTGCCTG CCGCTGCAGGAAACATTTCTGACACCGTCGACCAGGAAAGCCACACGGAGAGGCCACTGTGGGTGAAGC GCCTCAGTTACACAGGAACCCTAAAGCAAATCTGCCACCGTGGGGGAACTGACGCTGGAGATGCAAGGT GCTGGTGGGTCTGAGCTGGACGTCGCGGTGTGTCCTCTGTGCCCACGGTCTGAGCTAGCTAGCGCACCG CCGAGTTAAAGAGGAGAAGGAAAACATGCTGCTCTGGTGCACGCCTGAGCGTCCTCCATCTTCCAGGAT GGCAGCAATGGCGCTGTGCGGCCTCACCAGGCCCACGAGGAGCAGCAGCGCTCGGCCCGGAGCAGCAGG AAGGCCCCTCTGTGGAGCGCCCGCCGTCTGCTCCGGGGTGGTTCAGTCACTGCTTGTTGACATCAACAT GGCAATTGCACTCATGTGGACTGGGACCGTGCGAGCTGCCGTGTGGGTTAGTCGGGTGCCAGGACAATG AAATACTCCAGCACCTGTGGCTGACGAATTTGTTTCTACAGAAATAACAGCTGGGGACAACTGCGGTGA TGATGTAAAAACCTTCCCATAAAATGTAAGAAAAGCTGATGAGGCTGGTGACGTTCAGCCTTTGTCAAT AAACCTGTCATGTGCGGA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_001039966.2
Synonyms	CEPR; CMKRL2; DRY12; FEG-1; GPCR-Br; GPER; GPR30; LERGU; LERGU2; LyGPR; mER
Summary	This gene encodes a multi-pass membrane protein that localizes to the endoplasmic reticulum and a member of the G-protein coupled receptor 1 family. This receptor binds estrogen and activates multiple downstream signaling pathways, leading to stimulation of adenylate cyclase and an increase in cyclic AMP levels, while also promoting intracellular calcium mobilization and synthesis of phosphatidylinositol 3,4,5-trisphosphate in the nucleus. This protein therefore plays a role in the rapid nongenomic signaling events widely observed following stimulation of cells and tissues with estrogen. This receptor has been shown to play a role in diverse biological processes, including bone and nervous system development, metabolism, cognition, male fertility and uterine function. [provided by RefSeq, Aug 2017]
Locus ID	2852
MW	35.2

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