SPIRE2 (NM_032451) Human 3' UTR Clone

Specifications

Product Data
Product Name	SPIRE2 (NM_032451) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	Spir-2
ACCN	NM_032451
Insert Size	1077 bp
Sequence Data	Insert Sequence (showhide) >SC212091 3’UTR clone of NM_032451 The sequence shown below is from the reference sequence of NM_032451. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CCTAACACCAGGACTCTTGACTTCAAGTGACAGCCCCAGGTGGCCAGGCCTCCAGGAGGCACCAGGCAG GCCCTGTATCAGGCTAGGACGCTCTGAGCTGTGCATGTACATATATACATATATAGATACATTTATAAT ATATACACACAGTCTATATATTTATATACACTGTTTCCTGGCCCCAGAGCTCATTTGGGTTCAGGCGCA CTTCAAAACCCTCCCTGGGGGAGGCTGTTTCTTCTCAGGATTCCTTGCCAGGGAGGAAGGGGAGGGAAC AGGGTGGGTTTTCTCACTGAAGAGAGAAAGCAGAAGGTTCTAGATCCTGGCACAGACTGCATCCCATGT TCCCATGCTCTTCTCCGTCCCCAGGAATGCGAACGGCAGTTTCCCTTCCCCAGTGGACGTCTAGGTGGG GACAGGGTATCTTGGCTCCCAGCTGGACCAGAGTGCCCTGCTTGCCTCTGCTCTCCCTTTGTGGGGACT CAGGCAGCAGAGGCATCTGGGAAGTCTCTGAGTAGGCAGGGTCCTCCTGGGAGGCACCCCCACCTGTTT GAAAGGTCTGGCCAGGCGTGGTGGTTCAGGCCTGTAATTCCAGCACTTTGGGAGGCCGAGGAGGGAGGA TCACCTGAGGTCAGGAGTTTGAGACCAGCCTGGCCAACATGATGAAATGTTGTCTCTACTGAAAATGCA AAAATTAGCCAGGTATAGTGGCAGGAACCTGTAATCCCAGCTACAGGGGAGGCTGAGGCAGGAGAATCG CTTGAACCCGGGAGGTGTAGGTTGCAGTGAGCCGAGATTGCACCACTGCACTCCAGCCTGGGCGACAGA GCGAGACTCTGTCTCGAAAAAAAAAAAGGTCCGTGCCAAGCTGCTCCCTGCCCTTGCCCTTTCCCTTTC CCTGGGGTCCAAACCACATGTGTCCTGCCTCTCCTGGCCCTACCACATTCTGGTGCTGTCCTCACTCGC CCCTGGCCCAGAGGCTCCTGAAGATGCTGGGCGGTCCTGGCACAGGGAGGAGCAGCTCTGTAAATCTGT GCACATGGCCACTCTTGGCCTAATAAAGGAGGTCTCACAGTC ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_032451.2
Synonyms	Spir-2
Summary	Acts as an actin nucleation factor, remains associated with the slow-growing pointed end of the new filament (PubMed:21620703). Involved in intracellular vesicle transport along actin fibers, providing a novel link between actin cytoskeleton dynamics and intracellular transport (By similarity). Required for asymmetric spindle positioning and asymmetric cell division during meiosis (PubMed:21620703). Required for normal formation of the cleavage furrow and for polar body extrusion during female germ cell meiosis (PubMed:21620703). Also acts in the nucleus: together with SPIRE1 and SPIRE2, promotes assembly of nuclear actin filaments in response to DNA damage in order to facilitate movement of chromatin and repair factors after DNA damage (PubMed:26287480).[UniProtKB/Swiss-Prot Function]
Locus ID	84501
MW	39.2

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