TGF beta 3 (TGFB3) (NM_003239) Human 3' UTR Clone

Specifications

Product Data
Product Name	TGF beta 3 (TGFB3) (NM_003239) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	ARVD; ARVD1; LDS5; RNHF; TGF-beta3
ACCN	NM_003239
Insert Size	1120 bp
Sequence Data	Insert Sequence (showhide) >SC212349 3’UTR clone of NM_003239 The sequence shown below is from the reference sequence of NM_003239. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC ATGGTGGTGAAGTCTTGTAAATGTAGCTGAGACCCCACGTGCGACAGAGAGAGGGGAGAGAGAACCACC ACTGCCTGACTGCCCGCTCCTCGGGAAACACACAAGCAACAAACCTCACTGAGAGGCCTGGAGCCCACA ACCTTCGGCTCCGGGCAAATGGCTGAGATGGAGGTTTCCTTTTGGAACATTTCTTTCTTGCTGGCTCTG AGAATCACGGTGGTAAAGAAAGTGTGGGTTTGGTTAGAGGAAGGCTGAACTCTTCAGAACACACAGACT TTCTGTGACGCAGACAGAGGGGATGGGGATAGAGGAAAGGGATGGTAAGTTGAGATGTTGTGTGGCAAT GGGATTTGGGCTACCCTAAAGGGAGAAGGAAGGGCAGAGAATGGCTGGGTCAGGGCCAGACTGGAAGAC ACTTCAGATCTGAGGTTGGATTTGCTCATTGCTGTACCACATCTGCTCTAGGGAATCTGGATTATGTTA TACAAGGCAAGCATTTTTTTTTTTTTTTTAAAGACAGGTTACGAAGACAAAGTCCCAGAATTGTATCTC ATACTGTCTGGGATTAAGGGCAAATCTATTACTTTTGCAAACTGTCCTCTACATCAATTAACATCGTGG GTCACTACAGGGAGAAAATCCAGGTCATGCAGTTCCTGGCCCATCAACTGTATTGGGCCTTTTGGATAT GCTGAACGCAGAAGAAAGGGTGGAAATCAACCCTCTCCTGTCTGCCCTCTGGGTCCCTCCTCTCACCTC TCCCTCGATCATATTTCCCCTTGGACACTTGGTTAGACGCCTTCCAGGTCAGGATGCACATTTCTGGAT TGTGGTTCCATGCAGCCTTGGGGCATTATGGGTTCTTCCCCCACTTCCCCTCCAAGACCCTGTGTTCAT TTGGTGTTCCTGGAAGCAGGTGCTACAACATGTGAGGCATTCGGGGAAGCTGCACATGTGCCACACAGT GACTTGGCCCCAGACGCATAGACTGAGGTATAAAGACAAGTATGAATATTACTCTCAAAATCTTTGTAT AAATAAATATTTTTGGGGCATCCTGGATGATTTCATCTTCTGGAATATTGTTTCTAGAACAGTAAAAGC CTTATTCTAAGGTGTA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_003239.5
Synonyms	ARVD; ARVD1; LDS5; RNHF; TGF-beta3
Summary	This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGF-beta family members. This protein is involved in embryogenesis and cell differentiation, and may play a role in wound healing. Mutations in this gene are a cause of aortic aneurysms and dissections, as well as familial arrhythmogenic right ventricular dysplasia 1. [provided by RefSeq, Aug 2016]
Locus ID	7043
MW	41.4

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