SART1 (NM_005146) Human 3' UTR Clone

Specifications

Product Data
Product Name	SART1 (NM_005146) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	Ara1; HAF; HOMS1; SART1259; SNRNP110; Snu66
ACCN	NM_005146
Insert Size	1137 bp
Sequence Data	Insert Sequence (showhide) >SC212472 3’UTR clone of NM_005146 The sequence shown below is from the reference sequence of NM_005146. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC AGCATGAACGCGAACACCATCACCAAGTGACAGCGCCCTCCCGCCCCGGCCCTGCCTCAACCTTCATAT TAAATAAAGCTCCCTCCTTATTTTTTCCTCCCTGGTCGTGGTACAGATTCCAGGGTTGGATCTTTGGTT GGGTGTGGCACAGAGTCTGGCTCCTGCTAGGTGAGACCTGGCCATCAAATGACACAAACAACTAAACGA TGGAAGAGAGAGCGAGCCCGGGTCCTCTAAGGCTCCTTCCTTCTCCCCTGGCTGTCGGTCACACCTCTG CAGGGCCGGCTCTCTGATAGAAAGTGGAAGGCGGTTTTAGAAACTCATCACCCTGCTCTCTCCTGGCCT CGGGGGCTGCACAGGTCACTGTCCTGTAATGTCTCCCGGTCAGGGCAGCCCAGGACTGCCCAGCCTGGT GGGCTGGGGATTGGGCTTTGGGTAGGGCACAGGTGCCACCTTCTGTCCTGGCTGTCCTGTGCCACCCTG GTCTGTGTCTAGAGGAGTGAAACTCCCAGGGTTGGGCTGGGAGTATTTGGTGCACGCGGTATGGGGAGG GCTGAGCTCAGTGCCTCCTGGGAGACTTGTCCCGTGTACAGTGACCCAGAAAGATGAGATTCCTTGGCC TGAACTCTGTGATAGAGTGTGACTGAGCTGCTGGGGGACATGTGAGCCTCAAATCCATAGAAAGACAAA CGGCCACCTTGGGTGCCCAGGATACTGGTGCCTGGCCCCACGTACACCCACATACTTCTCAGATGGCTC CCACATTTTAAGATTTTAAAAATGAAACCAAAAAATAAATTGAAGAAAACTGTAAACTTTAAAGAATAA TCAGCTGGGCGCAGTGGCTCATGCTTGTAATCACAGCACTTTAGGAGGCTGAGGCAGGAGGACTGTTTG AGCCCAGGAGTTTGAGACCAACCTGAGTAAGGTGGCAAAACCCCATCTCTACCAAAAATACAAAGATTA GCCAGGCGTGGTGGTGAGCGCCTGTAGTCCCAGCTACTTGGGATGCTGAGGTGGGAGGATCACTTGAAC CTGGGAGACACAGGCTGCAGTGGGCCCTGATTGAGCCACCACACTGCAGCCTAGGTGACAGTCAGACCC TGTCTCAAAAAAAATAAAAAAAATTTAAAATAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_005146.5
Synonyms	Ara1; HAF; HOMS1; SART1259; SNRNP110; Snu66
Summary	This gene encodes two proteins, the SART1(800) protein expressed in the nucleus of the majority of proliferating cells, and the SART1(259) protein expressed in the cytosol of epithelial cancers. The SART1(259) protein is translated by the mechanism of -1 frameshifting during posttranscriptional regulation; its full-length sequence is not published yet. The two encoded proteins are thought to be involved in the regulation of proliferation. Both proteins have tumor-rejection antigens. The SART1(259) protein possesses tumor epitopes capable of inducing HLA-A2402-restricted cytotoxic T lymphocytes in cancer patients. This SART1(259) antigen may be useful in specific immunotherapy for cancer patients and may serve as a paradigmatic tool for the diagnosis and treatment of patients with atopy. The SART1(259) protein is found to be essential for the recruitment of the tri-snRNP to the pre-spliceosome in the spliceosome assembly pathway. [provided by RefSeq, Jul 2008]
Locus ID	9092
MW	42

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