CSNK1G2 (NM_001319) Human 3' UTR Clone

Specifications

Product Data
Product Name	CSNK1G2 (NM_001319) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	CK1g2
ACCN	NM_001319
Insert Size	1165 bp
Sequence Data	Insert Sequence (showhide) >SC212787 3’UTR clone of NM_001319 The sequence shown below is from the reference sequence of NM_001319. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC AAGAGAAAATCGCTGCAGCGACACAAGTGACCCTGGGCGCGTGCAGCCCCCTGAATCTTCTCCGTGCAG CCCCTTGGGGCGCGACCTTGTGCGAGGCCCTCGGGGCCCACCCACAGCGGCCCAGGGCCAGACCCTGGC TGGAAGCCAGAACGCAGACTGCAGGGGCCGCGCCTGGCTCAGGCGGCCCCACCCCCGGGACGTGGGGTC ACTTCCTTCATGTAAGACTTTGGCCGAAATTTCTACACCTGTGTCTAGTCCTCCCCTCCAAGAGCATTA ACTATTTAAAACAAGGAAAAGAGGAAAAAAAAAACAGAGGCCCGCCCTACCCCACTCCTGCCCCTCCGT TTCTTTGCTGAAGTGAGTAGTGTGATCCTGGAGGCCCCCCGGCCTGGCCCCGCCCCGCCAGCCGCCCCC GTTAGCGTCATAAAGTCCAGCTTGTCTCCCTCGATCCAAAGGCCGTTTTCTCGAGGGGAGGGCAGGCCC GGCCTGGAGGGGTGCTGTGGAGCTGTCTTGCCCAGGCCCTCCTGGGAGGGGGACAGGCATTGTTGCCAG GGGTGAGGCCGTGCCCCAGGCCTCCCCGAAACCAAAGGGGAAGGCAGGGGTGGGGCCGTGGCTGAAGCC GGCTCCCCAACCAAAATGCTGCACCAAAGCTCGGGCGCCGCGGGCACGGCTGCTGCAGTCTCTTCCCAG CCTGGCCCTGGCAAGGGGCGGGTGGGCGCTGCCAGGCGGGTGCTTCTCGACGCACTTGCTCCCGGAGGC TGCGCCCCGGCGCCTGGAACCCGAGGTGGGAGGACCGGTTGGTGTCACCCTGCTCGGCCCTCAGCCCTG CCGCGTGGGGCGCGTGGGCACGGAGCTTCCTGCCTCTCTGCTCCGACACCCGGCAAGCAGCCGGAGACA AAACGCCTTAAAGCCCCCGGCCCAGCCCTGCAGGTATATTGCAGGGGCCTGGGGGCGGCCCTGGACTGG CGGGCGGTTCCCCAGTGGGGTGCCCTGGAGGCTGCCGGGCAGAGTGGAGCAGCTTGGGGCCGTGCCCAG GGCGGTGGCTGTGAGTCTAGTTTTTGCTTTACCAAGTGTACAGAAATGGCATTTACGTTTCTCTGATGC TCCCTTGAAGCCATAGAATTTAGGGGCTTTTTTAAAAAAATAAAAGAAAAATGAAACCAAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_001319.7
Synonyms	CK1g2
Summary	Serine/threonine-protein kinase. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates COL4A3BP/CERT, MTA1 and SMAD3. Involved in brain development and vesicular trafficking and neurotransmitter releasing from small synaptic vesicles. Regulates fast synaptic transmission mediated by glutamate. SMAD3 phosphorylation promotes its ligand-dependent ubiquitination and subsequent proteasome degradation, thus inhibiting SMAD3-mediated TGF-beta responses. Hyperphosphorylation of the serine-repeat motif of COL4A3BP/CERT leads to its inactivation by dissociation from the Golgi complex, thus down-regulating ER-to-Golgi transport of ceramide and sphingomyelin synthesis. Triggers PER1 proteasomal degradation probably through phosphorylation.[UniProtKB/Swiss-Prot Function]
Locus ID	1455
MW	40.6

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