CA8 (NM_004056) Human 3' UTR Clone
CAT#: SC212818
3' UTR clone of carbonic anhydrase VIII (CA8) for miRNA target validation
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CNY 4,845.00
货期*
3周
规格
Cited in 2 publications. |
Product images
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经常一起买 (2)
Specifications
Product Data | |
Product Name | CA8 (NM_004056) Human 3' UTR Clone |
Vector | pMirTarget |
Synonyms | CA-RP; CA-VIII; CALS; CAMRQ3; CARP |
ACCN | NM_004056 |
Insert Size | 2000 bp |
Sequence Data |
>SC212818 3’UTR clone of NM_004056
The sequence shown below is from the reference sequence of NM_004056. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GACAGAGTCATTAGAGCTGCATTTCAGTAGCCAAAGAGGACAGGAACAAGTCTGTCTTCATGAGGGAGG AAGACAATGGTCCTATAATGCCCTTGGATAAGAAAAGGAAACTTTTGAGCTGCACCTTCAGTTTATCCT CAAAGCCTGCGTTGTTTGTCTTCATCTAATCCAGCTTTGATGGACATCTGTGATGGTTGCCTGTACACT TGCTGAAATGAAATATTAGAAATGGCTGTATATTCCAAAGAAACCCTATATTATATATCCACATTACTG CTGCTAGGATTCATAGTTGCACATACTGTTTATTGCTTATGTGTAGAAGGAATGAAACTAGTTTCCAGA GTTGTTATTAATATGAATATATATCATGTGTTAATATTGAGAAAGGAAAAATACATTCCCGGTGTTAGT AGTTCTTCATTTCCTGTCTCCAACAGAAAATTCACTCATTTTAGAACTAGTGTAATTCTTGATAATAAA ATAAGAGTTTTGATTAAGAACAGCATAGAGCTTCAAAATGCAAAGTGAATGATTAGTAAAATTATGTCT CATTTTATTTTTTCAGCACCCATACCACAATTAATATTAGGCTGGATTGCCATGGGAAACATTTTTTGG CATTAATGCAGCAACATAATACTCACTTTAGGTATTACTACATAGTTGAAGGATTTAACTGAATGTATG GATCAAATTTATTTATTTGACATATTCGAAGCTGTGGTTTAATAGGAATTTGAGAAAGGTGTAAGAAAT AGGATAAAAAGAAGGTCAGCACCATGTACCAGGAATAGCTTTACTTTCCATACATAGAAATATAAATTT AGTGGTATCCTATATTACTTTAGTGTCGTACGCTTTGTAAGACTTAAATATTTTATTCTATTGATTCCA CTACTTTGGTATGTTAAGACATTTCTTTAAAGATGACCAACAATATCCTTATTTTAGGTGCCACTAGCA GATGTAAGCGTATACTTAGTTGCCGTTAGATGTGACAGAATGAGATAATTTATGTAAAGCAGTAGAGTA CCTGGCACAAAGCAAACAATAAATATTATTGTTATTGTTGTTATAATTGTAAAATGAATGACTTCAAAA ACATAGTCCCAGTTTGGAGGGATTTTGTGATGCAGAATATCTAAGTCATAGAAATAGAAGACAGGTGGA ATAAGTATATGTTCAGAGTTTTTAGATGTGTTGAGTAGAGACGGTAATAATGGAAGCATTAAATACAAA TGAAAATCACACCAGATATCCCTGAAATTCAAGCAAAGAAAGTTCATCATGTATTCTTGGGCAGCAAGA GAAAGGACTAGGGTTATGGCAATGTGTGGAAAAGTTGAGGCTTGCTAAGGGTTGAGATCTGTTGGTAGC CCTGGATCACATGGGGTCAGCACCAGGCAGTGCCTCTGAAAGCGGAGAGAGGTCCTGGACTTCCCTTGT GTATAACAGTTCCTAGTGTCCAACAATGAGGAAACGGTGAAGCATGGTTACAAAACTGTGACAAAAATA TTTACATCTAGCACTGTTACCACTCACATGCCAAACATTGGCTGCACACGTGCAGCCTTATTTGTAATT AACATCAAAAGACTAGATCTGAAGCCTTCCATAAATGAGAGGCCATTCATATGGCATTCCTGGAACAAA ACACTGCACAGGTACCAGCCTCTCCACTCCTGACCGGGTTGGTGCTGAACAGTCAGGGATTGTTCTTGA ACTAGACTTCTGATGCTTCTTGCAATCTTCTTTCATCTTTCCCTGAAATACACAAAATAAACAAATACA ATAACAAATAGTAATTAAATGACTTTCAGGATAACATCTAGTTGTTCAGACTTCACCCTTCACAGGTGT GTGTGTATGTGTGTTTATGTCTGTATATTGAAGCAATTTGAATTTATTTACTGTATATTTTCTGAGTAA AAGACTGAAATGAACTACTTGGTTCAGATCATGGTGTCCATTGGTGACATTGTTTGGAGGCATAATAT ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG |
Restriction Sites | SgfI-MluI |
OTI Disclaimer | Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs). |
Reference Data | |
RefSeq | NM_004056.6 |
Synonyms | CA-RP; CA-VIII; CALS; CAMRQ3; CARP |
Summary | The protein encoded by this gene was initially named CA-related protein because of sequence similarity to other known carbonic anhydrase genes. However, the gene product lacks carbonic anhydrase activity (i.e., the reversible hydration of carbon dioxide). The gene product continues to carry a carbonic anhydrase designation based on clear sequence identity to other members of the carbonic anhydrase gene family. The absence of CA8 gene transcription in the cerebellum of the lurcher mutant in mice with a neurologic defect suggests an important role for this acatalytic form. Mutations in this gene are associated with cerebellar ataxia, mental retardation, and dysequilibrium syndrome 3 (CMARQ3). Polymorphisms in this gene are associated with osteoporosis, and overexpression of this gene in osteosarcoma cells suggests an oncogenic role. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016] |
Locus ID | 767 |
MW | 76.6 |
Citations (2)
The use of this cDNA Clones has been cited in the following citations: |
---|
Reversion mutation of cDNA CA8-204 minigene construct produces a truncated functional peptide that regulates calcium release in vitro and produces profound analgesia in vivo
,null,
Mammalian Genome
,PubMed ID 33247772
[CA8]
|
Profound analgesia is associated with a truncated peptide resulting from tissue specific alternative splicing of DRG CA8-204 regulated by an exon-level cis-eQTL
,null,
PLoS Genetics
,PubMed ID 31199789
[CA8]
|
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