Twinkle (TWNK) (NM_001163814) Human 3' UTR Clone

Specifications

Product Data
Product Name	Twinkle (TWNK) (NM_001163814) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	ATXN8; C10orf2; IOSCA; MTDPS7; PEO; PEO1; PEOA3; PRLTS5; SANDO; SCA8; TWINL
ACCN	NM_001163814
Insert Size	1273 bp
Sequence Data	Insert Sequence (showhide) >SC213517 3’UTR clone of NM_001163814 The sequence shown below is from the reference sequence of NM_001163814. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC TTTGGCTCAGCCAAAGTGAGTGGCCTTTAGCGGAGCTCAAGCTTTGGAAAATAGAGTGGGCAAGCCAGG AAGCAGACAATGTTCTGATCCTGCAGGACAGGAAGCTGGTAACCGGGCCAGGGAAACGGTATCTGCAGG TGTCCAAGAACCGCTTTGATGGAGATGTAGGTGTCTTCCCGCTTGAGTTCAACAAGAACTCCCTCACCT TCTCCATTCCACCAAAGAACAAGGCCCGGCTCAAGAAGATCAAGGATGACACTGGACCAGTGGCCAAAA AGCCCTCTTCTGGCAAAAAGGGGGCTACGACACAGAACTCTGAGATTTGCTCAGGCCAGGCCCCCACTC CCGACCAGCCAGACACCTCCAAGCGTTCAAAGTGAAGGCCGTGCAGAGCTGGTCACTGAAATGAGCCTG ATAGGATAGGCTGGAGCATAAAACTCTGCAAGGGCTCCTCTATCCTGTGGTCCTGAGCTGTGTGCCCTT CTCAGTCTGAGGGGCCTAACCTAGAGCAGGTTTCCATAGTGAGAAAATTCAATGTAGCAGACTACTGAG AAACTACTGTGTTGCTCAGGCTTTGTTTGAGGTCCTGTATATACAGCACTGAAAAGAGAGATAAAGTCC CTGCCTGCATGCATTCTGGCGGAAGAGACAAGCAAGCAATGAACAAATTAGCAGAAAACCTAGTTTTAG TGAAAAATGCTGTAAAGAAAATAGAAATGCGATAGAGTGCTGGCAGGCTAGTGTAGATAAGTGGTCTGA AAAGGTGTCTCTGAGCCGAGGGCATGTGAGCTGGGGCCTAAACAACTAGAAGGAGAGAGCCACGTGAAC ATCCGGCGAAGGGGACCCAGGCAGAGAGAAAAGGAAATCCAAGCCCTGAGGTAGGAATGAGCAGGTCAG ATTCAAGGCAGTGAGGTCAGGCCGCATGAACCTGGAGGGGAATCGGGGACTTCATGCGAAACTCCAGCC TAGGCTTTCAAAGTCAAAGGGTGATACAGTGGGTACCAAGCTCCTCTGCTCCCCACTTTGTAGAGCCTA GCATGAGGTGGCATGTACTAGAATTGGATCCTAGGTGCTTAGCCCTGCAATATCAGGGCCTCACTGGTG GGAGCTGCCTCGGGCTGGGTTGCTTGGTCATAGAGCCATAGAAGGAAGCTGTCAGCCCGGAGTGCCTGC CACCTAGACACTGATGCCATTGTGTGCTGCCTCAAGACTGCTGGAGTCAGGACATTTTATAGAGCCTTT TCCAGTTTTACTAAAAAATTTTTCCATTGCC ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_001163814.2
Synonyms	ATXN8; C10orf2; IOSCA; MTDPS7; PEO; PEO1; PEOA3; PRLTS5; SANDO; SCA8; TWINL
Summary	This gene encodes a hexameric DNA helicase which unwinds short stretches of double-stranded DNA in the 5' to 3' direction and, along with mitochondrial single-stranded DNA binding protein and mtDNA polymerase gamma, is thought to play a key role in mtDNA replication. The protein localizes to the mitochondrial matrix and mitochondrial nucleoids. Mutations in this gene cause infantile onset spinocerebellar ataxia (IOSCA) and progressive external ophthalmoplegia (PEO) and are also associated with several mitochondrial depletion syndromes. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Aug 2009]
Locus ID	56652
MW	46.5

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