P2X1 (P2RX1) (NM_002558) Human 3' UTR Clone
CAT#: SC213589
3' UTR clone of purinergic receptor P2X ligand-gated ion channel 1 (P2RX1) for miRNA target validation
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CNY 4,845.00
货期*
3周
规格
Cited in 3 publications. |
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经常一起买 (2)
Specifications
Product Data | |
Product Name | P2X1 (P2RX1) (NM_002558) Human 3' UTR Clone |
Vector | pMirTarget |
Synonyms | P2X1 |
ACCN | NM_002558 |
Insert Size | 1252 bp |
Sequence Data |
>SC213589 3’UTR clone of NM_002558
The sequence shown below is from the reference sequence of NM_002558. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GGCCTGCAGGAGAACATGAGGACATCCTGATGCTCGGGCCCCAACTCCTGACTGGGTGCAGCGTGAGGC TTCAGCCTGGAGCCCTGGTGGGTCCCAGCCAGGGCAGAGGGGCCTCCCCAGGAAGTCTCCTACCCTCTC AGCCAGGCAGAGAGCAGTTTGCCAGAAGCTCAGGGTGCATAGTAGGAGAGACCTGTGCAAATCTGAGCT CCGGCTCCGACCCCACACACCCTGAGGGAGCCCTACCCTAGCCTCAGCCGCTCCTGGTGGGGAATGGCT GGGGCTGGGCAGGACCCTCCCACACACCTGCACCCTAGCTTCGTGCTTCTCTCTCCGGACTCTCATTAT CCAACCCGCTGCCTCCATTTCTCTAGATCTGTGCTCTCCGATGTGGCAGTCAGTAACCATAGGTGACTA AATTAAACTAAAATAAAATAGAATGAAACACAAAATTCAATTCCTCGGCTGAACTAGCCACATTTCAAC TGCTCAGTAGATACGTGTGGTTAGTGGCTGCCATACTGGACAGCTCGGGGCATTTTCACTGTCAAAGAA AGTTCTATTAGACAGCCCTGCTTGAGCCCTGTTTCTTCCTGGCCTTCGGTTTCCCTGGGGAACTTATCG ACAATGCAAGCTCCTGGGCCCACCCCCAGACCTCCTGAACCAAAAGCTCCAGGGCTGGCCGTATGATCT GTGTGGATGGCAAACTCCCCAGGCCATTCTGGGACCTAAGTTTAAGAAGTGCCGTCCTCGAACTTTCTG ACTCTAAGCTCCTGAGCGGGAGTCAGACTTAGCCCTGAGCCTGCACTTCCTGTTCAGGTGCAGACACTG AACAGGGTCTCAAACACCTTCAGCATGTGTGTTGTGTGCTCACGTGCCACACAGTGTCTCATGCACACA ACCCAGTGTACACACCACCTACGTGCACACAGCATCCTTCCACACTGTGTATGTGAACAGCTTGGGCCC TGCAAACACAACCATCTACACACATCTACACCCCCAAGCACACACACATGGTCCGTGCCATGTCACCTC CATAGGGAAAGGCTTCTCTCCAAGTGTGCCAGGCCAGGACAGCCCTCCCAGCCATGAATCCTTACTCAG CTACCTCGGGTTGGGGTGGGAGCCCCAGCCAAATCCTGGGCTCCCTGCCTGTGGCTCAGCCCCAGCTCC CAAGGCCTGCCTGGCTCTGTCTGAACAGAAGGTCTGGGGGAAGCGACGGGTGGAGTACAATAAAGGGAA TGAGGACAAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG |
Restriction Sites | SgfI-MluI |
OTI Disclaimer | Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs). |
Reference Data | |
RefSeq | NM_002558.4 |
Synonyms | P2X1 |
Summary | The protein encoded by this gene belongs to the P2X family of G-protein-coupled receptors. These proteins can form homo-and heterotimers and function as ATP-gated ion channels and mediate rapid and selective permeability to cations. This protein is primarily localized to smooth muscle where binds ATP and mediates synaptic transmission between neurons and from neurons to smooth muscle and may being responsible for sympathetic vasoconstriction in small arteries, arterioles and vas deferens. Mouse studies suggest that this receptor is essential for normal male reproductive function. This protein may also be involved in promoting apoptosis. [provided by RefSeq, Jun 2013] |
Locus ID | 5023 |
MW | 45.1 |
Citations (3)
The use of this cDNA Clones has been cited in the following citations: |
---|
The role of agonist-induced activation and inhibition for the regulation of purinergic receptor expression in human platelets.
,null,
Thrombosis research
,PubMed ID 29902630
[P2RX1]
|
Pannexin-1 hemichannel-mediated ATP release together with P2X1 and P2X4 receptors regulate T-cell activation at the immune synapse
,null,
Blood
,PubMed ID 20660288
[P2RX1]
|
Genetic and functional analysis of human P2X5 reveals a distinct pattern of exon 10 polymorphism with predominant expression of the nonfunctional receptor isoform.
,null,
Molecular pharmacology
,PubMed ID 20223879
[P2RX1]
|
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