Pyruvate Kinase (PKLR) (NM_000298) Human 3' UTR Clone

Specifications

Product Data
Product Name	Pyruvate Kinase (PKLR) (NM_000298) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	PK1; PKL; PKRL; RPK
ACCN	NM_000298
Insert Size	1309 bp
Sequence Data	Insert Sequence (showhide) >SC213725 3’UTR clone of NM_000298 The sequence shown below is from the reference sequence of NM_000298. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC AACATCATGCGGGTGCTAAGCATATCCTGAGACGCCCCTCCCTCCTCTGGCCCAGCCTACCCTTGTACC CCATCCCTTCCTCCCCAGTCTACGTTCTCCAGCCCACACCCCTCCAAAGCCCCACCTTTAAGTCCTCTC TTCTCTATTCCTGACCCTCCCTACCTGAGGCCTATCTGAGACTATAACTGTCATCTAGCCCCTTCGAGG TTGCCCCTTCCCCATCTCCATTTCACACAGGTCCTGAAAGTCTGTGTCCAATTATGCACTGGCCACCCA ACAGCACCAATTGTACATTCCCTGCATCCAATCTGCTCAGCAGGCCCTAAGATGCCTTGAGTCTTTAAT CCCAGTTTGGCTGGTTAATTCCATAACCCCAGGCATCCCATCCCTTGGGGTGGGGGAGAGGGGAGACAG GGCAATCTTGTCCACAGTCTCCCATTCTCATATGTAGCCCTCATGATAATCTGGGCATCTCGTGCCAGG GCAGGCTACCCCTTCATGGTGACTAACAGTTACATGAAAGTCCACGCTTTTGGGAAAACTGGGTGGGAT GGATGCTGGGGAGAAGTGAGGGCTGGGCAGCTGATTTTGTCACTGTCTTCACAACCTCCGTGCTGGGCT TGTAGACCACTGTCCTGGCTGCTCTCATGCCTGCCTGATACCCTGCTTGGTCAAATCCCCGGCTGCTTC CTTCTGCACCCAGAAATTCCTTCCCACTCATGTTGTTCCCACACACAAACCAAGAGCCAAAAATGAGTG TGTCTATTTTATATTTAAACCCAGCTGTTTGGAAGCAATTATAAAACTTCTCCCACACACCAAGAACCC CAGAACTCCCCACCCAGAAGGAAAGGAGACTTAGGGTCCTGGTCCCACAGTCTTTAATGCTGTAGAGTA GGAGAGGGGACAGGCAGAGTGAGGGTGGTAAAGGACTACTCTTGTCCCTGAGAAGGCAGAGGTGCTGGC TGGCCTGCCCTTCCCCAGGCTTGGATACCTTGGGCCTTTCCCTTATTCCTGCACCAACAGCAAACTCAG AAGGAAAAAACAAAACAAAACTCTAAAGGTAAACGCGGTCCTTCTCCCTCTCTCATGTGGCTCCTCCTG CCCCTACCTGGGAGAAGGTTCAAGTATTGCGCTGATGGGTTTGGGCAAGGACCACAGAGGCTGGCATGG AGAGGCCCTGCCTCCTCCTACTCCTCCTGTCTCCTTACCTGAAAAGGAGGGGAGGGATGGATAAAGGAA TGGGTAAACAAAATTAATTGGTAACACATAAAGTTAGTAAATGAATAAATACAATTAAATAAATGAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_000298.6
Synonyms	PK1; PKL; PKRL; RPK
Summary	The protein encoded by this gene is a pyruvate kinase that catalyzes the transphosphorylation of phohsphoenolpyruvate into pyruvate and ATP, which is the rate-limiting step of glycolysis. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Locus ID	5313
MW	48.2

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