Calcium Sensing Receptor (CASR) (NM_000388) Human 3' UTR Clone

Specifications

Product Data
Product Name	Calcium Sensing Receptor (CASR) (NM_000388) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	CAR; EIG8; FHH; FIH; GPRC2A; hCasR; HHC; HHC1; HYPOC1; NSHPT; PCAR1
ACCN	NM_000388
Insert Size	2000 bp
Sequence Data	Insert Sequence (showhide) >SC213879 3’UTR clone of NM_000388 The sequence shown below is from the reference sequence of NM_000388. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC ACTGTTACAGAAAACGTAGTGAATTCATAAAATGGAAGGAGAAGACTGGGCTAGGGAGAATGCAGAGAG GTTTCTTGGGGTCCCAGGGAAGAGGAATCGCCCCAGACTCCTTTCCTCTGAGGAAGAAGGGATAATAGA CACATCAAATGCCCCGAATTTAGTCACACCATCTTAAATGACAGTGAATTGACCCATGTTCCCTTTAAA ATTAAAAAAAAGAAGAGCCTTGTGTTTCTGTGGTTGCATTTGTCAAAGCATTGAGATCTCCACGGTCAG ATTTGCTGTTCACCCACATCTAATGTCTCTTCCTCTGTTCTATCCCACCCAACAGCTCAGAGATGAAAC TATGGCTTTAAACTACCCTCCAGAGTGTGCAGACTGATGGGACATCAAATTTGCCACCACTAGAGCTGA GAGTCTGAAAGACAGAATGTCACCAGTCCTGCCCAATGCCTTGACAACAGACTGAATTTTAAATGTTCA CAACATAAGGAGAATGTATCTCCTCCTATTTATGAAAACCATATGATATTTTGTCTCCTACCTGCTGCT GCTATTATGTAACATCCAGAAGGTTTGCACCCCTCCTATACCATATGTCTGCTTCTGTCCAGGACATGA TACTGATGCCATGTTTAGATTCCAGGATCACAAGAATCACCTCAAATTGTTAGGAAGGGACTGCATAAA CCAATGAGCTGTATCTGTAATTAATATTCCTATATGTAGCTTTATCCTTAGGAAAATGCTTCTGTTGTA ATAGTCCATGGACAATATAAACTGAAAAATGTCAGTCTGGTTTATATAAGGCAGTATTATTGAGCTCTA TTTCCCCACCCCACTATCCTCACTCCCATAAGCTAAGCCTTATGTGAGCCCCTTCAGGGACTCAAGGGT CCAGAAGTCCCTCCCATCTCTACCCCAAAGAATTCCTGAAGCCAGATCCACCCTATCCCTGTACAGAGT AAGTTCTCAATTATTGGCCTGCTAATAGCTGCTAGGGTAGGAAAGCGTGGTTCCAAGAAAGATCCACCC TCAAATGTCAGAGCTATGTTCCCTCCAGCAGTGGTATTAATACTGCCGGTCACCCAGGCTCTGGAGCCA GAGAGACAGACCGGGGTTCAAGCCATGGCTTCGTCATTTGCAAGCTGAGTGACTGTAGGCAGGGAACCT TAACCTCTCTAAGCCACAGCTTCTTCATCTTTAAAATAAGGATAATAATCATTCTTTCCCCTCAGAGCT CTTATGTGGATTAAACGAGATAATGTATATAAAGTACTTTAGCCTGGTACCTAGCACACAATAAGCATT CAATAAATATTAGTTAATATTATTACTGATACTGTAATAATTATTTTTTCCCTTACTTCAAATACAAAA CAAAACATACATATTAACCATTCAGATTGTACTGCCTAGCCCACTGATCACAATCACTCTCTCTGTAAT AAGCCCAAGAGCTCTGGGCCCAACACATGGGGTCAGCCATAGTATCACTGGCTCATGGTGAGGAAGCCA GAAAGCTGGTCAGCCCCTCAGGTGGCCCAATGCCCTGTCTCCGCAGTGTCAGGGCCTGGACCTCCAGCA TCCAGGGAAGACCATCACCAGTCTAGCAGGAGGTTCTAAGCTGAGGCCAAACCATTGCAATTAAATCTC CTGAAGCCTCAAATTTTACAGCTCTTGGTGACTTCTTCCCCTGACCACTTTCTTCCAAAGGGGCGCCTT TCAGTGATTTGTAGGGCAAATTGGTGGACTTGATAGTTGTTAAGATTATAATGAGAAATCATTAGAGGG CACCATGTGGGAGCGCGACTGTGAGCAGAAGGTGGTGACTCAGGATGACCCAAGTGAGGTGCCTGCTCC CCACCTAGGAAGGGCACCGGCCCCCACCCAGCCTGCGCCCCCCTGCAGTCATGCCTCTGAGCAAGGCAC CGAGCTGAGTGGGGATTTATATTTAACATTTTACTTGGTCTTAAAAGAAATGCTGAAAATGTGATGGT ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_000388.4
Synonyms	CAR; EIG8; FHH; FIH; GPRC2A; hCasR; HHC; HHC1; HYPOC1; NSHPT; PCAR1
Summary	The protein encoded by this gene is a plasma membrane G protein-coupled receptor that senses small changes in circulating calcium concentration. The encoded protein couples this information to intracellular signaling pathways that modify parathyroid hormone secretion or renal cation handling, and thus this protein plays an essential role in maintaining mineral ion homeostasis. Mutations in this gene are a cause of familial hypocalciuric hypercalcemia, neonatal severe hyperparathyroidism, and autosomal dominant hypocalcemia. [provided by RefSeq, Aug 2017]
Locus ID	846
MW	74.2

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