SPTLC1 (NM_006415) Human 3' UTR Clone

Specifications

Product Data
Product Name	SPTLC1 (NM_006415) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	HSAN1; HSN1; LBC1; LCB1; SPT1; SPTI
ACCN	NM_006415
Insert Size	1348 bp
Sequence Data	Insert Sequence (showhide) >SC213918 3’UTR clone of NM_006415 The sequence shown below is from the reference sequence of NM_006415. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC AAGGAGGTAGCCCAGGCCGTCCTGCTCTAGGCAGAGTCCCGGGACCATGGCCTCCTGCCACACAACACG CAGAGAGGACTCAAGACTCCCGCTGGCCATGGAGTGGCCTGAAAGAGAGCAAGAACATGTGGATCTTTG ATAGGATTGTTACCAAATGGTGTCAGTATGGACCAATTGTGTGACCATGAGAAGGATGCTTATTTTTTT TAAAAAGAAAACACATCTAAAAGCCCAGGAACTGATTTTTTTAAGAGGAAAACTAATGACAGTGTATAA CTGATGTTTAAATTGTGCATTTAGTACTATTTAAATGTTTTCTTATACTAGTATTTTATATTCTTTTGT TGTCGTTTAAAACTGGAGCTTCAGTGTCTCTTCCCTCCCTCTAATAGTAATGGTTCAGTAAGCACTCCT TAACTCCTTAGTATTTCATAGAAAAATGACTGCAACATTAAAGCTAAGAGGAACACTTCAACATATGTG GTACAAATTTATATTGAAGATCTAAATAAACCACGTATTTTCCAGTCTTCGTTGTGTGAAGCTAAATGG TGGCTAAAAGGAACACTTTTTGTGTGATTATTATAAACTTTGCATTGTATTTGAATCTTAGAACTTTTG TACACACTAAATATTGATGTCACACCATTTCTAATCTGAGCATCCTTAGCCAGAGAATATTCATTATAC TTCCTAAGTGAGCAATAATTTAAATCAGAAGCTATTTTATTTTAATGTAATTAACCTTTCTTTACATTT CTTATGTGTTCACCTCTAATCTGTTTTAGGAAGAGAGTTGGTTATTATGTTGATCCCATAATATAAATC ATATCCTTTATATTTTAGAATATCTCAAATGTATTCCTTTTTTGTATGGTGGGTTTGCCTAGGGACGTG TAACTACAGGCTTTTACTAAGCCAAGGAAAAAGAGAATTTTTCTTTTCATCTTACAAATTCCAGATATC TACAAAAGATGTGAAAGCACTAAAAATACCATTTTTAAGCAGTACTTTACCTGTTTTTTCTTTAGCAAA CCAGGTTATGTGGTGTAAAGGTTTGTTATACGTGCCACAATATAGCATATAAATATTATGCCATCATTC CTTCTCTTGTTAAAGGTAGAAGAATAAAATTGTGATTTTTATAACCTGTGCTTATTACTCAAATGGTCT TCAACATCTTTTTAAACAACACATACTTTTTGAATGTTCAGTTTCTATTTTGCTTGAGGTATTTTGTAC ATATGTGCCTTGTGATTGCTGCTGCTTTAAAGGATAAAGTACTCTTTGGGGGATGAGTCTGGTTTGTTT TGTTTTATTTTTTAATGAAATAAACCTATATTCCTGA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_006415.4
Synonyms	HSAN1; HSN1; LBC1; LCB1; SPT1; SPTI
Summary	This gene encodes a member of the class-II pyridoxal-phosphate-dependent aminotransferase family. The encoded protein is the long chain base subunit 1 of serine palmitoyltransferase. Serine palmitoyltransferase converts L-serine and palmitoyl-CoA to 3-oxosphinganine with pyridoxal 5'-phosphate and is the key enzyme in sphingolipid biosynthesis. Mutations in this gene were identified in patients with hereditary sensory neuropathy type 1. Alternatively spliced variants encoding different isoforms have been identified. Pseudogenes of this gene have been defined on chromosomes 1, 6, 10, and 13. [provided by RefSeq, Jul 2013]
Locus ID	10558
MW	52.2

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