CD146 (MCAM) (NM_006500) Human 3' UTR Clone

Specifications

Product Data
Product Name	CD146 (MCAM) (NM_006500) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	CD146; HEMCAM; MelCAM; METCAM; MUC18
ACCN	NM_006500
Insert Size	1387 bp
Sequence Data	Insert Sequence (showhide) >SC214157 3’UTR clone of NM_006500 The sequence shown below is from the reference sequence of NM_006500. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GGAGAGAAATACATCGATCTGAGGCATTAGCCCCGAATCACTTCAGCTCCCTTCCCTGCCTGGACCATT CCCAGCTCCCTGCTCACTCTTCTCTCAGCCAAAGCCTCCAAAGGGACTAGAGAGAAGCCTCCTGCTCCC CTCGCCTGCACACCCCCTTTCAGAGGGCCACTGGGTTAGGACCTGAGGACCTCACTTGGCCCTGCAAGG CCCGCTTTTCAGGGACCAGTCCACCACCATCTCCTCCACGTTGAGTGAAGCTCATCCCAAGCAAGGAGC CCCAGTCTCCCGAGCGGGTAGGAGAGTTTCTTGCAGAACGTGTTTTTTCTTTACACACATTATGGCTGT AAATACCTGGCTCCTGCCAGCAGCTGAGCTGGGTAGCCTCTCTGAGCTGGTTTCCTGCCCCAAAGGCTG GCTTCCACCATCCAGGTGCACCACTGAAGTGAGGACACACCGGAGCCAGGCGCCTGCTCATGTTGAAGT GCGCTGTTCACACCCGCTCCGGAGAGCACCCCAGCAGCATCCAGAAGCAGCTGCAGTGTTGCTGCCACC ACCCTCCTGTCTGCCTCTTCAAAGTCTCCTGTGACATTTTTTCTTTGGTCAGAAGCCAGGAACTGGTGT CATTCCTTAAAAGATACGTGCCGGGGCCAGGTGTGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAG GCCGAGGCGGGCGGATCACAAAGTCAGGACGAGACCATCCTGGCTAACACGGTGAAACCCTGTCTCTAC TAAAAATACAAAAAAAAATTAGCTAGGCGTAGTGGTTGGCACCTATAGTCCCAGCTACTCGGAAGGCTG AAGCAGGAGAATGGTATGAATCCAGGAGGTGGAGCTTGCAGTGAGCCGAGACCGTGCCACTGCACTCCA GCCTGGGCAACACAGCGAGACTCCGTCTCGAGGAAAAAAAAAGAAAAGATACGTGCCTGCGGTGAGGAA GCTGGGCGCTGTTTTCGAGTTCAGGTGAATTAGCCTCAATCCCCCGTGTTCACTTGGCTCCCATAGCCC TCTTGATGGATCACGTAAAACTGAAAGGCAGCGGGGAGCAGACAAAGATGAGGTCTACACTGTCCTTCA TGGGGATTAAAGCTATGGTTATATTAGCACCAAACTTCTACAAACCAAGCTCAGGGCCCCAACCCTAGA AGGGCCCAAATGAGAGAATGGTACTTAGGGATGGAAAACGGGCCTGGCTAGAGCTTCGGGTGTGTGTGT CTGTCTGTGTGTATGCATACATATGTGTGTATATATGGTTTTGTCAGGTGTGTAAATTTGCAAATTGTT TCCTTTATATATGTATGTATATATATATATGAAAATATATATATATATGAAAAATAAAGCTTAATTGTC CCAGAAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_006500.3
Synonyms	CD146; HEMCAM; MelCAM; METCAM; MUC18
Summary	Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration.[UniProtKB/Swiss-Prot Function]
Locus ID	4162
MW	51.2

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