PIM1 (NM_002648) Human 3' UTR Clone

Specifications

Product Data
Product Name	PIM1 (NM_002648) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	PIM
ACCN	NM_002648
Insert Size	1367 bp
Sequence Data	Insert Sequence (showhide) >SC214258 3’UTR clone of NM_002648 The sequence shown below is from the reference sequence of NM_002648. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CACAGCCTGTCGCCGGGGCCCAGCAAATAGCAGCCTTTCTGGCAGGTCCTCCCCTCTCTTGTCAGATGC CCGAGGGAGGGGAAGCTTCTGTCTCCAGCTTCCCGAGTACCAGTGACACGTCTCGCCAAGCAGGACAGT GCTTGATACAGGAACAACATTTACAACTCATTCCAGATCCCAGGCCCCTGGAGGCTGCCTCCCAACAGT GGGGAAGAGTGACTCTCCAGGGGTCCTAGGCCTCAACTCCTCCCATAGATACTCTCTTCTTCTCATAGG TGTCCAGCATTGCTGGACTCTGAAATATCCCGGGGGTGGGGGGTGGGGGTGGGTCAGAACCCTGCCATG GAACTGTTTCCTTCATCATGAGTTCTGCTGAATGCCGCGATGGGTCAGGTAGGGGGGAAACAGGTTGGG ATGGGATAGGACTAGCACCATTTTAAGTCCCTGTCACCTCTTCCGACTCTTTCTGAGTGCCTTCTGTGG GGACTCCGGCTGTGCTGGGAGAAATACTTGAACTTGCCTCTTTTACCTGCTGCTTCTCCAAAAATCTGC CTGGGTTTTGTTCCCTATTTTTCTCTCCTGTCCTCCCTCACCCCCTCCTTCATATGAAAGGTGCCATGG AAGAGGCTACAGGGCCAAACGCTGAGCCACCTGCCCTTTTTTCTGCCTCCTTTAGTAAAACTCCGAGTG AACTGGTCTTCCTTTTTGGTTTTTACTTAACTGTTTCAAAGCCAAGACCTCACACACACAAAAAATGCA CAAACAATGCAATCAACAGAAAAGCTGTAAATGTGTGTACAGTTGGCATGGTAGTATACAAAAAGATTG TAGTGGATCTAATTTTTAAGAAATTTTGCCTTTAAGTTATTTTACCTGTTTTTGTTTCTTGTTTTGAAA GATGCGCATTCTAACCTGGAGGTCAATGTTATGTATTTATTTATTTATTTATTTGGTTCCCTTCCTATT CCAAGCTTCCATAGCTGCTGCCCTAGTTTTCTTTCCTCCTTTCCTCCTCTGACTTGGGGACCTTTTGGG GGAGGGCTGCGACGCTTGCTCTGTTTGTGGGGTGACGGGACTCAGGCGGGACAGTGCTGCAGCTCCCTG GCTTCTGTGGGGCCCCTCACCTACTTACCCAGGTGGGTCCCGGCTCTGTGGGTGATGGGGAGGGGCATT GCTGACTGTGTATATAGGATAATTATGAAAAGCAGTTCTGGATGGTGTGCCTTCCAGATCCTCTCTGGG GCTGTGTTTTGAGCAGCAGGTAGCCTGCTGGTTTTATCTGAGTGAAATACTGTACAGGGGAATAAAAGA GATCTTATTTTTTTTTTTATACTTGGCGTTTTTTGAATAAAAACCTTTTGTCTTAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_002648.4
Synonyms	PIM
Summary	The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons, the upstream non-AUG (CUG) and downstream AUG codons (PMIDs:16186805, 1825810).[provided by RefSeq, Aug 2011]
Locus ID	5292
MW	50.9

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