Caspase-7 (CASP7) (NM_033339) Human 3' UTR Clone
CAT#: SC214265
3' UTR clone of caspase 7 apoptosis-related cysteine peptidase (CASP7) transcript variant gamma for miRNA target validation
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CNY 4,845.00
货期*
3周
规格
Cited in 1 publication. |
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经常一起买 (2)
Specifications
Product Data | |
Product Name | Caspase-7 (CASP7) (NM_033339) Human 3' UTR Clone |
Vector | pMirTarget |
Synonyms | CASP-7; CMH-1; ICE-LAP3; LICE2; MCH3 |
ACCN | NM_033339 |
Insert Size | 1395 bp |
Sequence Data |
>SC214265 3’UTR clone of NM_033339
The sequence shown below is from the reference sequence of NM_033339. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CTCACCAAGGAACTCTACTTCAGTCAATAGCCATATCAGGGGTACATTCTAGCTGAGAAGCAATGGGTC ACTCATTAATGAATCACATTTTTTTATGCTCTTGAAATATTCAGAAATTCTCCAGGATTTTAATTTCAG GAAAATGTATTGATTCAACAGGGAAGAAACTTTCTGGTGCTGTCTTTTGTTCTCTGAATTTTCAGAGAC TTTTTTTATAATGTTATTCATTTGGTGACTGTGTAACTTTCTCTTAAGATTAATTTTCTCTTTGTATGT CTGTTACCTTGTTAATAGACTTAATACATGCAACAGAAGTGACTTCTGGAGAAAGCTCATGGCTGTGTC CACTGCAATTGGTGGTAACAGTGGTAGAGTCATGTTTGCACTTGGCAAAAAGAATCCCAATGTTTGACA AAACACAGCCAAGGGGATATTTACTGCTCTTTATTGCAGAATGTGGGTATTGAGTGTGATTTGAATGAT TTTTCATTGGCTTAGGGCAGATTTTCATGCAAAAGTTCTCATATGAGTTAGAGGAGAAAAAGCTTAATG ATTCTGATATGTATCCATCAGGATCCAGTCTGGAAAACAGAAACCATTCTAGGTGTTTCAACAGAGGGA GTTTAATACAGGAAATTGACTTACATAGATGATAAAAGAGAAGCCAAACAGCAAGAAGCTGTTACCACA CCCAGGGCTATGAGGATAATGGGAAGAGGTTTGGTTTCCTGTGTCCAGTAGTGGGATCATCCAGAGGAG CTGGAACCATGGTGGGGGCTGCCTAGTGGGAGTTAGGACCACCAATGGATTGTGGAAAATGGAGCCATG ACAAGAACAAAGCCACTGACTGAGATGGAGTGAGCTGAGACAGATAAGAGAATACCTTGGTCTCACCTA TCCTGCCCTCACATCTTCCACCAGCACCTTACTGCCCAGGCCTATCTGGAAGCCACCTCACCAAGGACC TTGGAAGAGCAAGGGACAGTGAGGCAGGAGAAGAACAAGAAATGGATGTAAGCCTGGCCCATAATGTGA ACATAAGTAATCACTAATGCTCAACAATTTATCCATTCAATCATTTATTCATTGGGTTGTCAGATAGTC TATGTATGTGTAAAACAATCTGTTTTGGCTTTATGTGCAAAATCTGTTATAGCTTTAAAATATATCTGG AACTTTTTAGATTATTCCAAGCCTTATTTTGAGTAAATATTTGTTACTTTTAGTTCTATAAGTGAGGAA GAGTTTATGGCAAAGATTTTTGGCACTTTGTTTTCAAGATGGTGTTATCTTTTGAATTCTTGATAAATG ACTGTTTTTTTCTGCCTAATAGTAACTGGTTAAAAAACAAATGTTCATATTTATTGATTAAAAATGTGG TTGCTTAATTCCTAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG |
Restriction Sites | SgfI-MluI |
OTI Disclaimer | Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs). |
Reference Data | |
RefSeq | NM_033339.5 |
Synonyms | CASP-7; CMH-1; ICE-LAP3; LICE2; MCH3 |
Summary | This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of the encoded protein is cleaved by caspase 3 and 10, is activated upon cell death stimuli and induces apoptosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012] |
Locus ID | 840 |
MW | 54.3 |
Citations (1)
The use of this cDNA Clones has been cited in the following citations: |
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Targeting the XIAP/caspase-7 complex selectively kills caspase-3-deficient malignancies
,null,
The Journal of Clinical Investigation
,PubMed ID 23979166
[CASP7]
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