PTP kappa (PTPRK) (NM_002844) Human 3' UTR Clone

Specifications

Product Data
Product Name	PTP kappa (PTPRK) (NM_002844) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	R-PTP-kappa
ACCN	NM_002844
Insert Size	1472 bp
Sequence Data	Insert Sequence (showhide) >SC214735 3’UTR clone of NM_002844 The sequence shown below is from the reference sequence of NM_002844. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GTAGCTTTGGAGTACCTGGAATCATCTTAGTTGGGTGAGACTCTTTAAAGTGCATCCATGAAGAAACCT GTCCATCTATTGAGCCAGCAGCTGTTGTACCTGTTACACTTGTGCAGAAAGATTTTAATGTGGGGGGTG GGAGACTTTTACATTTGAGAGGTAAAAGTATTTTTTTTATGAAGTTGTGTATCTTAATAAAAAGGACTG AATTAGTTTTTATTACTATATTAAAGCATCAACATTTCATGCCACATAAATTATATTTAATAAGAACCA GATTGAAATGAGAACGTATTGGTGTTTGTACAGTGAACATGCCACCTTTTTTCTCATGGTTTCAGTAGA GCAGCTACCACATGTTGCATGAGTTCATACTTTCTACGTGGCATTTTTCTCCCTTTCTAAAATGAAAGC TGATGAATCTTAAAAGGAAGAAGAAAAGAAAAGCTGTGCAAATTCATAGTAAAGTTCGTTTTTTATATG TTTCCAGTGTAGCAGATCTCTATATAAATATATAAATATATATAACTGGCTTATTTTCTTTTAATGTGC AATGATGGCTGGATCATTTAAAGTTCTTTTTAGAAAATAACATAAGCCAAAGACTCAAGTGTAAATATG TCTATATGGAGAAAGCACATTATATTTATTGGTTACTTACATTCCTTTTTTGATGGCTAAAATACTACC ACCACACAATCATCTTTTTTTTCCTGAAGAAAGCTTTTTCTTTAGCTAAAATCAATTGTAAACGATTTT TGTAGATTATTTTTTGTATGTTTTAGTGTAAGTAGAAGATAAACTTTTTATTCATAAACCAGGAAGCAA TGTTCTTTATAGTGATTCTCTTGTGTACATGCTTGTGAATTAAATTTGTGTAAAATCCCTTGGCAATTG GGTCTTTTAATATAGGACCAAATTAAAACATTTTGCTGAATATGTATAGTTTTTCACAATTTCATTAGG TAAATAATGGTTTGGTGATCATACATGAGAAATGTACACATTAAAAGGCCTTGCTGACAACTTGCACAA TGTTGAACATAGCCTTTAAGCATCATTTAAATTTTAAAGGAATGGAGTTTTTCAGCCTGTGGCCCAGCA CTGGTCAAGAAAACAAGATGGCAACATATATGCTTTCAGGGTCAAATTTGAGCAAACTGTAAACTGTCA GGGTGATAAAATGTTTCTCTTGATGTTTACATGCACAAGCTTTGCGTTCTGACTATAAAAAGTGTGAAC AAATCAATGCCAGATTCCTGTTTTGCGCATTGTCATGGGATTCTTAAGTGAACCTTTCTAAATGTGGTC TTGTTCACATGCTCCACGTAGCTGTAACTTCACATCATCAGCTTGCAGTTTGTAATTGACTAAAGCATT CCAGTGTCCTCTTTCTAGATTGCCAGCTCATGACATGGTGCTTATAAAGATTTAATTAAAGTAAGAATG AAATAAAGTTTTTATAATTATAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_002844.4
Synonyms	R-PTP-kappa
Summary	The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP was shown to mediate homophilic intercellular interaction, possibly through the interaction with beta- and gamma-catenin at adherens junctions. Expression of this gene was found to be stimulated by TGF-beta 1, which may be important for the inhibition of keratinocyte proliferation. [provided by RefSeq, Jul 2008]
Locus ID	5796
MW	56.8

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