PATZ1 (NM_032052) Human 3' UTR Clone

Specifications

Product Data
Product Name	PATZ1 (NM_032052) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	dJ400N23; MAZR; PATZ; RIAZ; ZBTB19; ZNF278; ZSG
ACCN	NM_032052
Insert Size	1502 bp
Sequence Data	Insert Sequence (showhide) >SC214770 3’UTR clone of NM_032052 The sequence shown below is from the reference sequence of NM_032052. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CCAGAAATGCTCACATCAGGATCCGATTGAGAGCTCTGACTCCTATGGTGACCTCTCAGATGCCAGCGA CCTGAAGACGCCAGAGAAGCAGAGTGCCAATGGCTCTTTCTCCTGCGACATGGCAGTCCCCAAAAACAA AATGGAGTCTGATGGGGAGAAGAAGTACCCATGCCCTGAATGTGGGAGCTTCTTCCGCTCTAAGTCCTA CTTGAACAAACACATCCAGAAGGTGCATGTCCGGGCTCTCGGGGGCCCCCTGGGGGACCTGGGCCCTGC CCTTGGCTCACCTTTCTCTCCTCAGCAGAACATGTCTCTCCTCGAGTCCTTTGGGTTTCAGATTGTTCA GTCGGCATTTGCGTCATCTTTAGTAGATCCTGAGGTTGACCAGCAGCCCATGGGGCCTGAAGGGAAATG AGGCAGCTGCTGTGTCCCCACGGAAACAACCATCTGGGGACTGCTGGGAAATGCTGTGAATGCGGAGGG AAGTGATGTTTGGGTTCTGTAGCTGAGAGATTTTTATTCATTTTTAACTGCCCCCCAACCCCACTCCAA CTCCTTCTCCACCACCCATTCTCCCAATGGTCTTTAGAAATAGATTTTCATCTGATATTCTGCAGAAAT ATCAATGAGACTTGGTATGGGACAGGGGCAGAAAACACTACATAGGCCTCCAAGGCAAAACCAGTCCCA GTTTCTTTAATGGGAAGAAGCTGGAATTCCTGGTGCTCAATTCTTAGTGACCCCAATCCTATACCCAAA TCTATGATATTCTGGGACCTCAGTGATTTTGGTCCCCTCCCACTTCTCTAGTTCGTCATCCTCCCTTCC CATATCCTTCAAAAGAACCACACTAGGGTCTCCACCTACTTATACAATGCGGATGCCCAACTGTTTTTA AGGAAGCCAGAAGCATCCCATGGACCATGGGGTGAGTGTCCTCCAAGAGCCCCCTGAGCTCAGCCCTCT GCCTGGAGGGCTCCAGACCTTTCTGAGCCCTGCTTGGAGGCGAGCATTTTCACTGCTAGGACAAGCTCA GCTGTTGAGGACACCCCCACCCCAAATTTCAGTTCTTACGTGATTTTAACCATTCAACATGCTGTTGGG TTTTAATTCTCTAATTATTATTATTATTGTTATTATTTTTTAGGACCAGTTGTAGTGAATTGCTACTGA AAGCTATCCCAGGTGATACAGAGCTCTTTGTAAACCGCAGTCACACATTAGGGTTAGTATTAAACTTTG TTTAGATGTACCATAATTAACTTGGCTAGTTGATTGTTTGAAGTCTATGGAAGAAATAGTTTTATGCAA AATTTTAAAAAATGCCAGTCTGGTCAGGGAAGTAGGGGGTTTCAATGCTGTTGGGAACCAGGAAGGTGG GACAGCCGGCAGGTAGGGACATTGTGTACCTCAGTTGTGTCACATGTGAGCAAGCCCAGGTTGACCTTG TGATGTGAATTGATCTGATCAGACTGTATTAAAAATGTTAGTACATTACTCTA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_032052.2
Synonyms	dJ400N23; MAZR; PATZ; RIAZ; ZBTB19; ZNF278; ZSG
Summary	The protein encoded by this gene contains an A-T hook DNA binding motif which usually binds to other DNA binding structures to play an important role in chromatin modeling and transcription regulation. Its Poz domain is thought to function as a site for protein-protein interaction and is required for transcriptional repression, and the zinc-fingers comprise the DNA binding domain. Since the encoded protein has typical features of a transcription factor, it is postulated to be a repressor of gene expression. In small round cell sarcoma, this gene is fused to EWS by a small inversion of 22q, then the hybrid is thought to be translocated (t(1;22)(p36.1;q12). The rearrangement of chromosome 22 involves intron 8 of EWS and exon 1 of this gene creating a chimeric sequence containing the transactivation domain of EWS fused to zinc finger domain of this protein. This is a distinct example of an intra-chromosomal rearrangement of chromosome 22. Four alternatively spliced transcript variants are described for this gene. [provided by RefSeq, Jul 2008]
Locus ID	23598
MW	55.9

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