Cytochrome P450 1A2 (CYP1A2) (NM_000761) Human 3' UTR Clone

Specifications

Product Data
Product Name	Cytochrome P450 1A2 (CYP1A2) (NM_000761) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	CP12; CYPIA2; P3-450; P450(PA)
ACCN	NM_000761
Insert Size	1549 bp
Sequence Data	Insert Sequence (showhide) >SC215008 3’UTR clone of NM_000761 The sequence shown below is from the reference sequence of NM_000761. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CAGGCGCGGCTGCGCTTCTCCATCAATTGAAGAAGACACCACCATTCTGAGGCCAGGGAGCGAGTGGGG GCCAGCCACGGGGACTCAGCCCTTGTTTCTCTTCCTTTCTTTTTTTAAAAAATAGCAGCTTTAGCCAAG TGCAGGGCCTGTAATCCCAGCATTTTAGGAGGCCAAGGTTGGAGGATCATTTGAGCCCAGGAATTGGAA AGCAGCCTGGCCAACATAGTGGGACCCTGTCTCTACAAAAAAAAAATTTGCCAAGAGCCTGAGTGACAG AGCAAGACCCCATCTCAAAAAAAAAAACAAACAAACAAAAAAAAAACCATATATATACATATATATATA GCAGCTTTATGGAGATATAATTCTTATGCCATATAATTCACCTTCTTTTTTTTTTTTTGTCTGAGACAG AATCTCAGTCTGTCACCCAGGTTGGAGTGCAGTGGCGTGATCTCAGCTCACTGCAACCTCCACCTCGCA GGTTCAAGCAATCCTCCCACTTCAGCCTCCCAAGCACCTGGGATTACAAGCATGAGTCACTACGCCTGG CTGATTTTTGTAGTTTTAGTGGAGATGGGGTTTCACCATGTTGGCCAGGCTTGTCTCGAACTCCTGACC CCAAGTTATCCACCTGCCTTGGCTTCCCAAAGTCCTGGGATTACAGGTGTGAGCCACCACATCCAGCCT AACTTACATTCTTAAAGTGTCGAATGACTTCTAGTGTAGAATTGTGCAACCATCACCAGAATTAATTTT ATTATTCTTATTATTTTTGAGACAGAGTCTTACTCTGTTGCCAGGCTGGAGTGCAGTGGCGCGATCTCA GCTCACTACAACCTCCGCCTCCCATGTTCAAGCGATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACT ATAGGCATGCGCCACCATGGCCAGCTAATTTTTGTATTTTTAGTAGAGACGAGGTTTCACTGTGTTGGC CAGGATGGTCTCCATCTCTTGACCTCGTGATCCACCCGCCTCAGCCTCCCAAAGTGCTGGGATTAACAG GTATGAACCACCGCGCCCAGCCTTTTTGTTTTTTTTTTTTTTGAGACAGAGTCTTCCTCTGTCTCCTAA GCTGGAGTGCAGTGGCATCATCTCAGCTCACTGCAACCTCTGCCTCCCAGGTTCAAGTGCTTCTCCAGC CTCAGCCTCCCAAGTAGCTGAGACTACAGGCACACACCACCACGCCTGGCTAATTTTTGTATTTTTAGT AGAGACGGGTTTCACCATGTTGGCTAGACTAGTCTCAAACTCCTGACCTCAAGTGATCTGCCCGCCTCG ACCTCTCTCAAAGTGCTGGCATTACAGGTGTGAGCCACGGTGCCCGGCCCACAATTAATTTTAGAACAT TTTCATCACCCCTAAAAGAAACCCTGCACCCATTAGCAGTCCCTCCACATTTCCCCCTAGCCTGCCTCC CCTGCCTCACCAGCCCTGGCAACTGCTAATCTACTTTCTGTGTCTATGGATTTGCCTTCTCTAAACATT TCATATAAATGGAATTACACAATGAGTGGTC ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_000761.5
Synonyms	CP12; CYPIA2; P3-450; P450(PA)
Summary	This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. Other xenobiotic substrates for this enzyme include caffeine, aflatoxin B1, and acetaminophen. The transcript from this gene contains four Alu sequences flanked by direct repeats in the 3' untranslated region. [provided by RefSeq, Jul 2008]
Locus ID	1544
MW	57

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