RBM25 (NM_021239) Human 3' UTR Clone

Specifications

Product Data
Product Name	RBM25 (NM_021239) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	fSAP94; NET52; RED120; RNPC7; S164; Snu71
ACCN	NM_021239
Insert Size	2000 bp
Sequence Data	Insert Sequence (showhide) >SC215317 3’UTR clone of NM_021239 The sequence shown below is from the reference sequence of NM_021239. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GAAGCCAAGAAAATTGGTCTTGTGAAGTAAAACTTTTTATATTTAGAGTTCCATTTCAGATTTCTTCTT TGCCACCCTTTTAAGGACTTTGAATTTTTCTTTGTCTTTGAAGACATTGTGAGATCTGTAATTTTTTTT TTTTGTAGAAAATGTGAATTTTTTGGTCCTCTAATTTGTTGTTGCCCTGTGTACTCCCTTGGTTGTAAA GTCATCTGAATCCTTGGTTCTCTTTATACTCACCAGGTACAAATTACTGGTATGTTTTATAAGCCGCAG CTACTGTACACAGCCTATCTGATATAATCTTGTTCTGCTGATTTGTTTCTTGTAAATATTAAAACGACT CCCCAATTATTTTGCAGAATTGCACTTAATATTGAAATGTACTGTATAGGAACCAACATGAACAATTTT AATTGAAAACACCAGTCATAAACTATTACCACCCCCACTCTCTTTTGATCAGAAATGGCAAGCCCTTGT GAAGGCATGGAGTTTAAAATTGGAATGCAAAAATTAGCAGACAATCCATTCCTACTGTATTTCTGTATG AATGTGTTTGTGAATGTATGTGTAAAAGTCTTTCTTTTCCCTAATTTGCTTTGGTGGGGTCCTTAAAAC ATTTCCCAACTAAAGAATAGAATTGTAAAGGAAAAGTGGTACTGTTCCAACCTGAAATGTCTGTTATAA TTAGGTTATTAGTTTCCCAGAGCATGGTGTTCTCGTGTCGTGAGCAATGTGGTTTGCTAACTGGATGGG GTTTTCTTATTAATAAGATGGCTGCTTCAGCTTCTCTTTTAAAGGAATGTGGATCATAGTGATTTTTCC TTTTAATTTTATTGCTCAGAAATGAGGCATATCCTAAAAATCCTGGAGAGCTGTATTTAATGCATTTTT GCACTAATTGGTCCTTAGTTTAATTCTATTGTATCTGTTTATTTAACAAAAAATTCATCATACCAAAAA GTGTAAGTGAAAACCCCCTTTAAAACAAAACAAAAAAATGAAATAAAATTAGGCAAATTGACAGACAGT GAGAGTTTTACAAACATGATAGGTATTCTGCTCGGCAATTTGTAAGTTTACATGTTATTTAAGGATAAA GGTAAATCATTCAAGGCAGTTACCAACCACTAACTATTTGTTTTCATTTTTGTCTTGTAGAAGGTTTAT ATCTTGTTTTACCTTGGCTCATTAGTGTTTAAAAATGTACTGATGATGTGCTTAGAGAAATTCCTGGGG CTTTCTTCGTTGTAGATCAGAATTTCACCAGGGAGTAAAATTACCTGAAAACGTAAGAAGTTTTAAACA GCTTTTCACACAAATTAGATGCAACTGTTCCCATGTCTGAGTACTTATTTAAAAGAAAGGTAAAGATTG GCCTGTTAGAAAAAGCATAATGTGAGCTTTGGATTACTGGATTTTTTTTTTTTTTAAACACACCTGGAG AGGACATTTGAAAACACTGTTCTTACCCTCGAACCCTGATGTGGTTCCATTATGTAAATATTTCAAATA TTAAAAATGTATATATTTGATCCTGGGGACTCATATTCTTTCAGAATCATGTAAATAAATGGCATCATG TTGTAATTGTGTGGTGCATACTAGAAAAGTTAAAAATATGGGCTGAACTTTTTATGGACTTGATTTTTA TGACTATTGGTATCTAAAGGTCAAGGAAGCCATTTACATTATTTTGGATGAATCTACTATACATCTATG GAAATGTCTCTTTTATTTTAAATTCTGGTTTCTCAACGGAAAATTTCAGAAAAGATGCCCCTTGCCATT TTCGTTAATTTTTCAGTCTTTTCTTAGACACACCCCCAGCCTAAGACCTTGTTCGAGGAGTTTATTGTG TCTGTCTTTTCTTAACATACTGCACTGTTCTTAAGCATCATATTGTGTTGTTTTTATTTAGCCACTATT AACATGAAGGTTTATTCAGGTAGATTTGATTTCCTTTGCTTCGTTTCTTCTCCTGCTCTGTCAACTGT ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_021239.3
Synonyms	fSAP94; NET52; RED120; RNPC7; S164; Snu71
Summary	RNA-binding protein that acts as a regulator of alternative pre-mRNA splicing. Involved in apoptotic cell death through the regulation of the apoptotic factor BCL2L1 isoform expression. Modulates the ratio of proapoptotic BCL2L1 isoform S to antiapoptotic BCL2L1 isoform L mRNA expression. When overexpressed, stimulates proapoptotic BCL2L1 isoform S 5'-splice site (5'-ss) selection, whereas its depletion caused the accumulation of antiapoptotic BCL2L1 isoform L. Promotes BCL2L1 isoform S 5'-ss usage through the 5'-CGGGCA-3' RNA sequence. Its association with LUC7L3 promotes U1 snRNP binding to a weak 5' ss in a 5'-CGGGCA-3'-dependent manner. Binds to the exonic splicing enhancer 5'-CGGGCA-3' RNA sequence located within exon 2 of the BCL2L1 pre-mRNA. Also involved in the generation of an abnormal and truncated splice form of SCN5A in heart failure.[UniProtKB/Swiss-Prot Function]
Locus ID	58517
MW	77.4

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