Caspase 3 (CASP3) (NM_032991) Human 3' UTR Clone

Specifications

Product Data
Product Name	Caspase 3 (CASP3) (NM_032991) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	CPP32; CPP32B; SCA-1
ACCN	NM_032991
Insert Size	1606 bp
Sequence Data	Insert Sequence (showhide) >SC215501 3’UTR clone of NM_032991 The sequence shown below is from the reference sequence of NM_032991. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CTCACAAAAGAACTCTATTTTTATCACTAAAGAAATGGTTGGTTGGTGGTTTTTTTTAGTTTGTATGCC AAGTGAGAAGATGGTATATTTGGTACTGTATTTCCCTCTCATTTTGACCTACTCTCATGCTGCAGAGGG TACTTTAAGACATACTCCTTCCATCAAATAGAACCACTATGAAGCTACCTCAAACTTCCAGTCAGGTAG TTGCAATTGAATTAAATTAGGAATAAATAAAAATGGATACTGGTGCAGTCATTATGAGAGGCAATGATT GTTAATTTACAGCTTTCATGATTAGCAAGTTACAGTGATGCTGTGCTATGAATTTTCAAGTAATTGTGA AAAAGTTAAACATTGAAGTAATGAATTTTTATGATATTCCCCCCACTTAAGACTGTGTATTCTAGTTTT GTCAAACTGTAGAAATGATGATGTGGAAGAACTTAGGCATCTGTGGGCATGGTCAAAGGCTCAAACCTT TATTTTAGAATTGATATACACGGATGACTTAACTGCATTTTTAGACCATTTATCTGGGATTATGGTTTT GTGATGTTTGTCCTGAACACTTTTGTTGTAAAAAAATAATAATAATGTTTAATATTGAGAAAGAAACTA ATATTTTATGTGAGAGAAAGTGTGAGCAAACTAACTTGACTTTTAAGGCTAAAACTTAACATTCATAGA GGGGTGGAGTTTTAACTGTAAGGTGCTACAATGCCCCTGGATCTACCAGCATAAATATCTTCTGATTTG TCCCTATGCATATCAGTTGAGCTTCATATACCAGCAATATATCTGAAGAGCTATTATATAAAAACCCCA AACTGTTGATTATTAGCCAGGTAATGTGAATAAATTCTATAGGAACATATGAAAATACAACTTAAATAA TAAACAGTGGAATATAAGGAAAGCAATAAATGAATGGGCTGAGCTGCCTGTAACTTGAGAGTAGATGGT TTGAGCCTGAGCAGAGACATGACTCAGCCTGTTCCATGAAGGCAGAGCCATGGACCACGCAGGAAGGGC CTACAGCCCATTTCTCCATACGCACTGGTATGTGTGGATGATGCTGCCAGGGCGCCATCGCCAAGTAAG AAAGTGAAGCAAATCAGAAACTTGTGAAGTGGAAATGTTCTAAAGGTGGTGAGGCAATAAAAATCATAG TACTCTTTGTAGCAAAATTCTTAAGTATGTTATTTTCTGTTGAAGTTTACAATCAAAGGAAAATAGTAA TGTTTTATACTGTTTACTGAAAGAAAAAGACCTATGAGCACATAGGACTCTAGACGGCATCCAGCCGGA GGCCAGAGCTGAGCCCTCAGCCCGGGAGGCAGGCTCCAGGCCTCAGCAGGTGCGGAGCCGTCACTGCAC CAAGTCTCACTGGCTGTCAGTATGACATTTCACGGGAGATTTCTTGTTGCTCAAAAAATGAGCTCGCAT TTGTCAATGACAGTTTCTTTTTTCTTACTAGACCTGTAACTTTTGTAAATACACATAGCATGTAATGGT ATCTTAAAGTGTGTTTCTATGTGACAATTTTGTACAAATTTGTTATTTTCCATTTTTATTTCAAAATAT ACATTCAAACTTAAAATTA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_032991.3
Synonyms	CPP32; CPP32B; SCA-1
Summary	The protein encoded by this gene is a cysteine-aspartic acid protease that plays a central role in the execution-phase of cell apoptosis. The encoded protein cleaves and inactivates poly(ADP-ribose) polymerase while it cleaves and activates sterol regulatory element binding proteins as well as caspases 6, 7, and 9. This protein itself is processed by caspases 8, 9, and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. [provided by RefSeq, Aug 2017]
Locus ID	836
MW	61.1

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